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Your Position: Home > Glycoprotein D (HSV-2)

Glycoprotein D (HSV-2)

Brief Information

Name:Envelope glycoprotein D
Target Synonym:
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 2 Clinical

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Part of Bioactivity data

GLD-M609-ELISA
 Glycoprotein D (HSV-2) ELISA

Immobilized HSV-1 (strain 17) Envelope Glycoprotein D (gD), His Tag (Cat. No. GLD-V52H3) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-HSV-2-Glycoprotein D Antibody, Human IgG1 (3H9) (Cat. No. GLD-M609) with a linear range of 1-31 ng/mL (QC tested).

GLD-V52H4-MALS-HPLC
Glycoprotein D (HSV-2) MALS images

The purity of HSV-2 (strain HG52) Envelope Glycoprotein D (gD), His Tag (Cat. No. GLD-V52H4) is more than 90% and the molecular weight of this protein is around 40-55 kDa verified by SEC-MALS.

Synonym Name

gD

Background

Herpesvirus infections are widely spread throughout the world population. Herpes simplex virus (HSV) belongs to the α-herpesvirus subfamily. There are two main types of HSV, HSV-1 and HSV-2, which infect humans. HSV-2 mainly causes genital lesions, whereas HSV-1 is involved in both oral and genital infections. Glycoprotein D (gD) is a structural component of the herpes simplex virus type 1 (HSV-1) envelope which is essential for virus entry and fusion with host cells. gD plays an important role by binding to the host receptors such as herpes virus entry mediator (HVEM) and nectin-1, a member of the immunoglobulin (Ig)-like cell adhesion molecules.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
UB-621 UB-621 Phase 2 Clinical United Biopharma Inc Herpes Simplex; Herpes Genitalis Details

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