Login Register
icon_bulk_orderBulk order Acrobiosystems for English
There is no goods in the shopping cart !
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Home > Complement Factor D

Complement Factor D

Brief Information

Name:Complement factor D
Target Synonym:EC 3.4.21,EC 3.4.21 );,C3 Convertase Activator,ADIPSIN,D Component Of Complement (Adipsin),PFD,Complement Factor D Preproprotein,Complement Factor D (Adipsin),EC,ADN,CFD,Properdin factor D,DF,Complement factor D,EC:
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:4
Lastest Research Phase:Phase 3 Clinical

Product ListCompare or Buy

Synonym Name

CFD,Adipsin,PFD,DF,Complement factor D


Complement factor D (CFD) is also known as Adipsin, C3 convertase activator, Properdin factor D (PFD), which contains one peptidase S1 domain and belongs to the peptidase S1 family. CFD / Adipsin cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. CFD / Adipsin is a serine protease that stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis. Defects in CFD / Adipsin are the cause of complement factor D deficiency which predisposes to invasive meningococcal disease.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
ACH-5548 ACH-5548; ACH-0145548 Phase 1 Clinical Achillion Pharmaceutical Autoimmune Diseases Details
BCX-9930 BCX-9930 Phase 1 Clinical Biocryst Pharmaceuticals Hemoglobinuria, Paroxysmal Details
Danicopan ACH-4471; ACH-0144471; ALXN-2040 Phase 3 Clinical Achillion Pharmaceutical Hemoglobinuria, Paroxysmal; Renal Insufficiency; Glomerulonephritis, Membranoproliferative; Hepatic Insufficiency; Geographic Atrophy; Glomerulonephritis Details
Vemircopan ACH-0145228; ACH-5228; ALXN-2050 Phase 2 Clinical Achillion Pharmaceutical Myasthenia Gravis; Glomerulonephritis, IGA; Hemoglobinuria, Paroxysmal; Kidney Diseases; Lupus Nephritis; Hepatic Insufficiency Details

This web search service is supported by Google Inc.

Call us
Call us
North America: +1 800-810-0816 (Toll Free)
Asia & Pacific: +86 400-682-2521
+1 888-377-6111
1 Innovation Way, Newark, DE 19711, USA

Leave a message