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M-CSF R

M-CSF R Protein Product ListCompare or Buy

Cat. No. Species Product Description Structure Purity Feature
CSR-R82H5 Rabbit Rabbit M-CSF R / CSF1R / CD115 Protein, His Tag
CSR-R82H5-structure
CSR-C82H3 Canine Canine M-CSF R / CSF1R / CD115 Protein, His Tag
CSR-C82H3-structure
CSR-M82E8 Mouse Biotinylated Mouse M-CSF R / CSF1R / CD115 Protein, His Tag & Avi Tag (Avitag™)
CSR-M82E8-structure
CSR-M82E8-sds
CSR-M82E8-elisa_1
CSR-H82E0 Human Biotinylated Human M-CSF R / CSF1R / CD115 Protein, Avi Tag (Avitag™)
CSR-H82E0-structure
CSR-H82E0-sds
CSR-H82E0-elisa_1
CSR-C5252 Cynomolgus Cynomolgus M-CSF R / CSF1R / CD115 Protein, Fc Tag
CSR-C5252-structure
CSR-C5252-sds
CSR-C52E1 Cynomolgus Cynomolgus M-CSF R / CSF1R / CD115 Protein
CSR-C52E1-structure
CSR-C52E1-sds
CSR-M5256 Mouse Mouse M-CSF R / CSF1R / CD115 Protein, Fc Tag, low endotoxin
CSR-M5256-structure
CSR-M5256-sds
CSR-M5256-elisa_1
CSR-M52E7 Mouse Mouse M-CSF R / CSF1R / CD115 Protein
CSR-M52E7-structure
CSR-M52E7-sds
CSR-M52E7-elisa_1
CSR-H5258 Human Human M-CSF R / CSF1R / CD115 Protein, Fc Tag, low endotoxin
CSR-H5258-structure
CSR-H5258-sds
CSR-H5258-elisa_1
CSR-H5228 Human Human M-CSF R / CSF1R / CD115 Protein
CSR-H5228-structure
CSR-H5228-sds

M-CSF R Molecule Synonym Name

CSF1R,C-FMS,CD115,CSFR,FIM2,FMS,M-CSFR

M-CSF R Molecule Background

Colony stimulating factor 1 receptor (CSF1R) is also known as macrophage colony-stimulating factor receptor (M-CSFR), CD115 Cluster of Differentiation 115 (CD115), C-FMS, CSFR, FIM2, FMS, and is a member of the type¢ó subfamily of receptor tyrosine kinases (RTKs). CSF1R is a receptor for a cytokine called colony stimulating factor 1, The protein encoded by the CSFR1 gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most, if not all, of the biological effects of this cytokine. Ligand binding activates CSFR1 through a process of oligomerization and transphosphorylation . Mutations in CSF1R are associated with chronic myelomonocytic leukemia and type M4 acute myeloblastic leukemia. Increased levels of CSF1R1 are found in microglia in Alzheimer's disease and after brain injuries. The increased receptor expression causes microglia to become more active. Both CSF1R, and its ligand colony stimulating factor 1 play an important role in the development of the mammary gland and may be involved in the process of mammary gland carcinogenesis.

M-CSF R References

M-CSF R Related Molecule

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