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Cathepsin D

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Cat. No. Species Product Description Structure Purity Feature
CAD-H52H3 Human Human Cathepsin D Protein, His Tag (active enzyme, MALS verified)
CAD-H52H3-structure
CAD-H52H3-sds
ACRO Quality

Part of Bioactivity data

CAD-H52H3-MALS-HPLC
Cathepsin D MALS images

The purity of Human Cathepsin D Protein, His Tag (Cat. No. CAD-H52H3) is more than 90% and the molecular weight of this protein is around 45-65 kDa verified by SEC-MALS.

Synonym Name

CTSD,Cathepsin D,CPSD,CLN10

Background

Cathepsin D is also known as CTSD, CPSD, which belongs to the peptidase A1 family. Cathepsin D can be cleaved into the following 2 chains: cathepsin D light chain and cathepsin D heavy chain, which is expressed in the aorta extrcellular space (at protein level). The catalytic activity of Cathepsin D is specificity similar to, but narrower than, that of pepsin A. Cathepsin D does not cleave the 4-Gln-|-His-5 bond in B chain of insulin. Cathepsin D involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.

Clinical and Translational Updates

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