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Your Position: Home > Cathepsin S

Cathepsin S

Brief Information

Name:Cathepsin S
Target Synonym:EC:3.4.22.27,Cathepsin S,CTSS,EC 3.4.22,EC 3.4.22.27
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Discontinued

Synonym Name

CTSS,Cathepsin S

Background

Cathepsin S is also known as CTSS, which is a member of the peptidase C1 family. Cathepsin S is a lysosomal cysteine protease that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. Cathepsin S can function as an elastase over a broad pH range in alveolar macrophages. The catalytic activity of cathepsin S is similar to cathepsin L, but with much less activity on Z-Phe-Arg-|-NHMec, and more activity on the Z-Val-Val-Arg-|-Xaa compound.

Clinical and Translational Updates

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