Name:Cathepsin S Target Synonym:EC:22.214.171.124,Cathepsin S,CTSS,EC 3.4.22,EC 126.96.36.199
Number of Launched Drugs:0 Number of Drugs in Clinical Trials:0 Lastest Research Phase:Discontinued
Cathepsin S is also known as CTSS, which is a member of the peptidase C1 family. Cathepsin S is a lysosomal cysteine protease that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. Cathepsin S can function as an elastase over a broad pH range in alveolar macrophages. The catalytic activity of cathepsin S is similar to cathepsin L, but with much less activity on Z-Phe-Arg-|-NHMec, and more activity on the Z-Val-Val-Arg-|-Xaa compound.