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Your Position: Home > Cathepsin S

Cathepsin S

Cathepsin S Molecule Information

Name:Cathepsin S
Target Synonym:CTSS;Cathepsin S

Number of Launched Drugs:0
Number of Drugs in Clinical Trials:13
Lastest Research Phase:Phase ?

Cathepsin S Protein Product ListCompare or Buy

Product> Filter Results

Cat. No.	Species	Product Description	Structure	Purity	Feature
CTS-H5224	Human	Human Cathepsin S / CTSS Protein, His Tag

Cathepsin S Molecule Synonym Name

CTSS,Cathepsin S

Cathepsin S Molecule Background

Cathepsin S is also known as CTSS, which is a member of the peptidase C1 family. Cathepsin S is a lysosomal cysteine protease that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. Cathepsin S can function as an elastase over a broad pH range in alveolar macrophages. The catalytic activity of cathepsin S is similar to cathepsin L, but with much less activity on Z-Phe-Arg-|-NHMec, and more activity on the Z-Val-Val-Arg-|-Xaa compound.

Cathepsin S References

Burkard T.R., et al., 2011, BMC Syst. Biol. 5:17-17.

Cathepsin S Clinical Drug Information

Name	Research Code	Research Phase	Company	Indications	Clinical Trials
VBY-036	VBY-036,VBY036	Phase Ⅰ	ViroBay	Neuropathic pain, Crohn's disease	Details
RWJ-445380	RWJ-445380	Phase Ⅱ	Johnson & Johnson	Plaque psoriasis, Rheumatoid arthritis (RA)	Details
AM-3840	AM-3840	Preclinical	Amura Therapeutics	Neuropathic pain, Rheumatoid arthritis (RA)	Details
Cz-007		Preclinical	Merck	Trypanosoma cruzi infection	Details
VBY-825	VBY-106; VBY-285; VBY-825	Preclinical	ViroBay	Neuropathic pain, Bone cancer, Autoimmune diseases, Alzheimer's disease (AD)	Details
VBY-129	VBY-129,VBY129	Phase Ⅰ	ViroBay	Neuropathic pain, Crohn's disease	Details
SAR-114137	SAR 114137; SAR114137	Phase Ⅰ	Sanofi	Neuropathic pain, Pain	Details
VBY-891	VBY-891,VBY891	Phase Ⅰ	ViroBay, Leo Pharma	Neuropathic pain, Psoriasis	Details
Petesicatib	RG-7625; RO-5459072	Phase Ⅱ	Roche	Psoriasis, Sjoegren's syndrome	Details
LY-3000328	LY-3000328,LY3000328	Phase Ⅰ	Lilly	Abdominal aortic aneurysm	Details
MIV-247	MIV-247,MIV 247,MIV247	Preclinical	Medivir	Neuropathic pain, Autoimmune diseases, Multiple sclerosis (MS), Rheumatoid arthritis (RA)	Details
CRA-028129	CRA-028129	Phase Ⅰ	Celera, Bayer	Psoriasis	Details
RG-7236	RG7236; RG 7236	Phase Ⅰ	Roche	Cardiovascular disorders	Details