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Growth Hormone R

Growth Hormone R Protein Product ListCompare or Buy

Cat. No. Species Product Description Structure Purity Feature
GHR-C5253 Rhesus macaque Rhesus macaque Growth Hormone R (GHR) Protein, Fc Tag
GHR-C5253-structure
GHR-C5253-sds
GHR-C5253-elisa_1
GHR-H8222 Human Biotinylated Human Growth Hormone R, ultra sensitivity (primary amine labeling)
GHR-H8222-structure
GHR-H8222-sds
GHR-H8222-elisa_1
GHR-H5257 Human Human Growth Hormone R (GHR) Protein, Fc Tag
GHR-H5257-structure
GHR-H5257-sds
GHR-H5257-elisa_1
GHR-H5222 Human Human Growth Hormone R (GHR) Protein, His Tag
GHR-H5222-structure
GHR-H5222-sds
GHR-H5222-elisa_1

Growth Hormone R Molecule Synonym Name

GHR,GHBP,GH receptor

Growth Hormone R Molecule Background

Growth hormone receptor (GHR) is also known as somatotropin receptor, growth hormone-binding protein (GHBR), which belongs to the type I cytokine receptor family or Type 1 subfamily. GHR contains one fibronectin type-III domain. GHR / GHBR is expressed in various tissues with high expression in liver and skeletal muscle. The soluble form (GHBP) is produced by phorbol ester-promoted proteolytic cleavage at the cell surface (shedding) by ADAM17/TACE. GHR is receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway. The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.

Growth Hormone R References

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