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Growth Hormone R

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Growth Hormone R Part of Bioactivity data

GHR-H8222-ELISA
Biotinylated Human GHR, His Tag, ultra sensitivity (primary amine labeling)Biotinylated Human GHR, His Tag, ultra sensitivity (primary amine labeling) (Cat. No. GHR-H8222) ELISA bioactivity

Immobilized Human GH, Tag Free at 2 μg/mL (100 μL/well) can bind Biotinylated Human GHR, His Tag, ultra sensitivity (primary amine labeling) (Cat. No. GHR-H8222) with a linear range of 0.5-8 ng/mL (QC tested).

GHR-C5253-ELISA
Rhesus macaque GHR, Fc TagRhesus macaque GHR, Fc Tag (Cat. No. GHR-C5253) ELISA bioactivity

Immobilized Human GH, Tag Free at 2 μg/mL (100 μL/well) can bind Rhesus macaque GHR, Fc Tag (Cat. No. GHR-C5253) with a linear range of 0.039-0.625 μg/mL (QC tested).

Growth Hormone R Molecule Synonym Name

GHR,GHBP,GH receptor

Growth Hormone R Molecule Background

Growth hormone receptor (GHR) is also known as somatotropin receptor, growth hormone-binding protein (GHBR), which belongs to the type I cytokine receptor family or Type 1 subfamily. GHR contains one fibronectin type-III domain. GHR / GHBR is expressed in various tissues with high expression in liver and skeletal muscle. The soluble form (GHBP) is produced by phorbol ester-promoted proteolytic cleavage at the cell surface (shedding) by ADAM17/TACE. GHR is receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway. The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.

Growth Hormone R References

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