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B7-H5

B7-H5 Protein Product ListCompare or Buy

B7-H5 Part of Bioactivity data

B75-H5258-SPR
Human_FcRn_Heterodimer_Protein_SPR

Human B7-H5, Mouse IgG2a Fc Tag, low endotoxin (Cat. No. B75-H5258) Captured on CM5 chip via anti-mouse antibodies surface can bind Human VSIG3, Fc Tag (Cat. No. VS3-H5258) with an affinity constant of 8.87 μM as determined in a SPR assay (Biacore T200) (Routinely tested).

B75-H52H0-SPR
Human_FcRn_Heterodimer_Protein_SPR

Captured Human VSIG3 Protein, Fc Tag on CM5 chip via Anti-human IgG Fc antibodies surface can bind Human B7-H5, His Tag (Cat. No. B75-H52H0) with an affinity constant of 31.5 μM as determined in a SPR assay (Biacore T200) (Routinely tested).

B7-H5 Molecule Synonym Name

B7-H5,SISP1,Gi24,VISTA

B7-H5 Molecule Background

Platelet receptor Gi24, also known as B7-H5 and stress-induced secreted protein-1 (Sisp-1), is a protein that in humans is encoded by the C10orf54 gene, which contains 1 Ig-like (immunoglobulin-like) domain. As for C10orf54 gene, C10orf54 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state on ESCs. Human C10orf54 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.

B7-H5 References

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