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Your Position: Home > IL-18 R1

IL-18 R1

Brief Information

Name:Interleukin-18 receptor 1
Target Synonym:IL-1Rrp,IL-18R-1,CD218a,IL-18Ralpha,IL1 receptor-related protein,IL-18R1,CDw218a,IL-18R-alpha,Interleukin-18 receptor alpha,CD218 antigen-like family member A,IL1R-rp
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:

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Part of Bioactivity data

IL1-H82E7-SPR
Human_FcRn_Heterodimer_Protein_SPR

Biotinylated Human IL-18 R1, His,Avitag (Cat. No. IL1-H82E7) captured on Biotin CAP-Series S Sensor Chip can bind Human IL-18, Tag Free (Cat. No. IL8-H5113) with an affinity constant of 1.49 μM as determined in a SPR assay (Biacore 8K) (QC tested).

IL1-H82E7-SPR
Human_FcRn_Heterodimer_Protein_SPR

Biotinylated Human IL-18 R1, His,Avitag (Cat. No. IL1-H82E7) captured on Biotin CAP-Series S Sensor Chip can bind Human IL-18, Tag Free (Cat. No. IL8-H5113) (Premixed with Human IL-18 R beta / IL-1 R7, Fc Tag, Cat. No. ILB-H5256) with an affinity constant of 5.87 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

Synonym Name

IL18R1,IL1RRP,CD218a,IL18Ra

Background

Interleukin-18 receptor 1 (IL18R1) is also known as CD218 antigen-like family member A (CD218a), IL1 receptor-related protein (IL-1Rrp or IL1R-rp), CDw218a, IL18Ra, IL1RRP, which belongs to the interleukin-1 receptor family. IL18R1 contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL18R1 is receptor for interleukin 18 (IL-18). IL18R1 binds to the agonist leads to the activation of NF-kappa-B, but does not bind IL1A/interleukin-1 alpha or IL1B/interleukin-1 beta.

Clinical and Translational Updates

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