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LIF Molecule Information

Name:Leukemia inhibitory factor
Target Synonym:LIF Interleukin 6 Family Cytokine,D factor,Emfilermin,LIF,Differentiation-stimulating factor,LIF, Interleukin 6 Family Cytokine,Differentiation Inhibitory Activity,Cholinergic Differentiation Factor,Hepatocyte-Stimulating Factor III,Differentiation-Induci
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Discontinued

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Cat. No. Species Product Description Structure Purity Feature
LIF-H82E2 Human Biotinylated Human LIF Protein, His,Avitag™
LIF-M5227 Mouse Mouse LIF Protein, His Tag
LIF-H521b Human ActiveMax® Human LIF Protein, Tag Free

LIF Part of Bioactivity data

ActiveMax® Human LIF, Tag FreeActiveMax® Human LIF, Tag Free (Cat. No. LIF-H521b) ELISA bioactivity

Immobilized ActiveMax® Human LIF, Tag Free (Cat. No. LIF-H521b) at 0.2 μg/mL (100 μL/well) can bind Human LIF R, Fc Tag (Cat. No. LIR-H4252) with a linear range of 4-63 ng/mL (QC tested).

Biotinylated Human LIF, His,AvitagBiotinylated Human LIF, His,Avitag (Cat. No. LIF-H82E2) ELISA bioactivity

Immobilized Biotinylated Human LIF, His,Avitag (Cat. No. LIF-H82E2) on SA-coated surface at 1 μg/mL (100 μL/well) can bind Human LIF R, Fc Tag (Cat. No. LIR-H4252) with a linear range of 1-31 ng/mL (QC tested).

LIF Molecule Synonym Name


LIF Molecule Background

Leukemia inhibitory factor, or LIF, an interleukin 6 class cytokine, is a protein in cells that affects cell growth and development.Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Removal of LIF pushes stem cells toward differentiation, but they retain their proliferative potential or pluripotency. Therefore LIF is used in mouse embryonic stem cell culture. It is necessary to maintain the stem cells in an undifferentiated state, however genetic manipulation of embryonic stem cells allows for LIF independent growth, notably overexpression of the gene Nanog. LIF is not required for culture of human embryonic stem cells.

LIF References

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