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LTBR

LTBR Molecule Information

Name:Tumor necrosis factor receptor superfamily member 3
Target Synonym:Lymphotoxin-beta receptor?TNFRSF3?Tumor necrosis factor receptor superfamily member 3?Tumor necrosis factor receptor 2-related protein?TNFR-III?TNFR3?Tumor necrosis factor C receptor?Tumor necrosis factor receptor type III?D12S370 ?TNF-RIII?TNFCR?LTBR
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase ?

LTBR Protein Product ListCompare or Buy

Cat. No. Species Product Description Structure Purity Feature
LTR-H5251 Human Human LTBR / TNFRSF3 Protein, Fc Tag
LTR-H5251-structure
LTR-H5251-sds

LTBR Molecule Synonym Name

LTBR,D12S370,TNFCR,TNFR3,TNFRSF3,TNFRIII

LTBR Molecule Background

Lymphotoxin-beta receptor (LTBR) is also known as Tumor necrosis factor receptor superfamily member 3 (TNFRSF3), Tumor necrosis factor receptor type III (TNF-RIII), which is a single-pass type I membrane protein containing four TNFR-Cys repeat regions. Except for interacting with HCV core protein, LTBR can not only associate with itself, but also can associate with TRAF3, TRAF4 and TRAF5. As the receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT, LTBR promotes apoptosis via TRAF3 and TRAF5. Furthermore, LTBR may play a role in the development of lymphoid organs.

LTBR References

LTBR Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Baminercept BG 9924; LTβR-Ig Phase Ⅱ Biogen, National Institute of Allergy and Infectious Diseases Sjoegren's syndrome Details

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