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MICA

MICA Protein Product ListCompare or Buy
Cat. No. Species Product Description Structure Purity Feature
MIA-H5221 Human Human MICA Protein
MIA-H5221-structure
MIA-H5221-sds

MICA Molecule Synonym Name

MIC-A

MICA Molecule Background

MHC class I polypeptide-related sequence A (MICA) belongs to the MHC class I family and MIC subfamily. MICA contains one Ig-like C1-type (immunoglobulin-like) domain. Unlike classical MHC class I molecules, MICA does not form a heterodimer with beta-2-microglobulin. MICA acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. MICA is ligand for the KLRK1/NKG2D receptor. MICA bind to KLRK1 leads to cell lysis.

MICA References

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