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MICA

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Cat. No. Species Product Description Structure Purity Feature
MIA-H5253 Human Human MICA Protein, Fc Tag
MIA-H5253-structure
MIA-H5253-sds
MIA-H5253-elisa_1
MIA-H5221 Human Human MICA Protein, His Tag (MALS verified)
MIA-H5221-structure
MIA-H5221-sds
MIA-H5221-elisa_1

Part of Bioactivity data

MIA-H5221-ELISA
Human MICA, His TagHuman MICA, His Tag (Cat. No. MIA-H5221) ELISA bioactivity

Immobilized Human MICA, His Tag (Cat. No. MIA-H5221) at 5 μg/mL (100 μL/well) can bind Human NKG2D, Fc Tag (HPLC-verified) (Cat. No. NKD-H5265) with a linear range of 2-31 ng/mL (QC tested).

MIA-H5221-MALS-HPLC
Human MICA, His Tag (Cat. No. ) MALS images

The purity of Human MICA, His Tag (Cat. No. MIA-H5221) is more than 90% and the molecular weight of this protein is around 55-70 kDa verified by SEC-MALS.

Bioactivity-ELISA
Human MICA, His TagHuman MICA, His Tag (Cat. No. MIA-H5221) ELISA bioactivity

Immobilized Human MICA, His Tag (Cat. No. MIA-H5221) at 5 μg/mL (100 μL/well) can bind Human NKG2D, Fc Tag (HPLC-verified) (Cat. No. NKD-H5265) with a linear range of 2-31 ng/mL (QC tested).

Synonym Name

MIC-A

Background

MHC class I polypeptide-related sequence A (MICA) belongs to the MHC class I family and MIC subfamily. MICA contains one Ig-like C1-type (immunoglobulin-like) domain. Unlike classical MHC class I molecules, MICA does not form a heterodimer with beta-2-microglobulin. MICA acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. MICA is ligand for the KLRK1/NKG2D receptor. MICA bind to KLRK1 leads to cell lysis.

Clinical and Translational Updates

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