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Part of Bioactivity data

Biotinylated Human MICA, His,AvitagBiotinylated Human MICA, His,Avitag (Cat. No. MIA-H82E6) ELISA bioactivity

Immobilized Biotinylated Human MICA, His,Avitag (Cat. No. MIA-H82E6) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Human NKG2D, Fc Tag (Cat. No. NKD-H5265) with a linear range of 0.3-10 ng/mL (QC tested).

MICA MALS images

The purity of Biotinylated Human MICA Protein, Fc,Avitag (Cat. No. MIA-H82F6) is more than 90% and the molecular weight of this protein is around 145-175 kDa verified by SEC-MALS.

Synonym Name



MHC class I polypeptide-related sequence A (MICA) belongs to the MHC class I family and MIC subfamily. MICA contains one Ig-like C1-type (immunoglobulin-like) domain. Unlike classical MHC class I molecules, MICA does not form a heterodimer with beta-2-microglobulin. MICA acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. MICA is ligand for the KLRK1/NKG2D receptor. MICA bind to KLRK1 leads to cell lysis.

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