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Spare 1 minute for the survey of bispecific antibody, get the gift of your choice from us!
FACS assay shows that recombinant Human OX40, Mouse IgG2a Fc Tag, low endotoxin (Cat. No. OX0-H5252) can bind to 293T cell overexpressing human OX40L. The concentration of OX40 is 0.01 μg/mL (Routinely tested).
Loaded Biotinylated Human OX40, Avitag,His Tag (Cat. No. TN4-H82E4) on SA Biosensor, can bind Anti-OX40 MAb (Human IgG1) with an affinity constant of 0.115 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).
Loaded Biotinylated Human OX40, Avitag,His Tag (Cat. No. TN4-H82E4) on SA Biosensor, can bind Human OX40 Ligand, His Tag (active trimer) (MALS verified) (Cat. No. OXL-H52Q8) with an affinity constant of 0.127 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).
| Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
|---|---|---|---|---|---|
| SL-279252 | TAK-252; SL-279252 | Phase 1 Clinical | Shattuck Labs | Carcinoma, Renal Cell; Squamous Cell Carcinoma of Head and Neck; Esophageal Neoplasms; Lymphoma, Large B-Cell, Diffuse; Carcinoma, Transitional Cell; Hodgkin Disease; Melanoma; Adenocarcinoma; Carcinoma, Non-Small-Cell Lung | Details |
| MEDI-6469 | MEDI-6469 | Phase 2 Clinical | Providence Cancer Center, Agonox | Head and Neck Neoplasms; Lymphoma, Large B-Cell, Diffuse; Breast Neoplasms; Prostatic Neoplasms; Colorectal Neoplasms; Lymphoma; Melanoma | Details |
| Vonlerolizumab | RG-7888; MOXR-0916; RO-7021608 | Phase 1 Clinical | Genentech Inc | Carcinoma, Transitional Cell; Neoplasms | Details |
| FS-120 | FS-120 | Phase 1 Clinical | F-Star | Neoplasms; Neoplasm Metastasis | Details |
| KHK-4083 | KHK-4083 | Phase 2 Clinical | Kyowa Hakko Kirin Co Ltd | Abdominal Pain; Gastrointestinal Diseases; Inflammatory Bowel Diseases; Autoimmune Diseases; Colitis; Colitis, Ulcerative; Colonic Diseases; Dermatitis, Atopic; Intestinal Diseases | Details |
| ATOR-1015 | ADC-1015; ATOR-1015 | Phase 1 Clinical | Alligator Bioscience | Neoplasms | Details |
| GBR-830 | GBR-830 | Phase 2 Clinical | Glenmark Pharmaceuticals Ltd | Dermatitis, Atopic | Details |
| INCAGN-1949 | INCAGN-1949 | Phase 2 Clinical | Agenus Inc, Ludwig Institute For Cancer Research | Carcinoma, Renal Cell; Urogenital Neoplasms; Neoplasm Metastasis | Details |
| Recombinant human anti-OX40 monoclonal antibody (Eucure Biopharma) | YH-002 | Phase 1 Clinical | Eucure Pharmaceutical Technology (Beijing) Co Ltd | Solid tumours | Details |
| PF-04518600 | PF-8600; PF-04518600 | Phase 2 Clinical | Pfizer Pharmaceuticals Ltd (China) | Carcinoma, Renal Cell; Neoplasms; Lymphoma, Follicular; Breast Neoplasms; Leukemia, Myeloid, Acute; Carcinoma, Squamous Cell | Details |
| Recombinant human anti-OX40 monoclonal antibody (Livzon Group) | Phase 1 Clinical | Livzon Pharmaceutical Group Inc | Neoplasms | Details | |
| GSK3174998 | GSK3174998; GSK 3174998; GSK-3174998 | Phase 2 Clinical | Glaxosmithkline Plc | Head and Neck Neoplasms; Neoplasms; Multiple Myeloma | Details |
| mRNA-2416 | mRNA-2416; OX40L mRNA - Moderna Therpeutics | Phase 2 Clinical | Moderna Therapeutics | Ovarian Neoplasms; Solid tumours; Lymphoma | Details |
| Cudarolimab | IBI-101 | Phase 1 Clinical | Innovent Biologics(Suzhou) Co Ltd | Solid tumours | Details |
| BAT-6026 | BAT-6026 | Phase 1 Clinical | Shanghai Cp Guojian Pharmaceutical Co Ltd, Bio-Thera Solutions Ltd | Solid tumours | Details |
| BGB-A445 | BGB-A445 | Phase 1 Clinical | Beigene Ltd | Solid tumours | Details |
| BMS-986178 | BMS-986178 | Phase 2 Clinical | Bristol-Myers Squibb Company | Neoplasms | Details |
| INBRX-106 | INBRX-106; ES-102; ES102 | Phase 1 Clinical | Inhibrx | Solid tumours; Head and Neck Neoplasms; Carcinoma, Renal Cell; Stomach Neoplasms; Carcinoma, Transitional Cell; Carcinoma, Non-Small-Cell Lung; Melanoma | Details |
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