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SIRP gamma

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Part of Bioactivity data

SIG-H5253-ELISA
Human SIRP gamma, Fc TagHuman SIRP gamma, Fc Tag (Cat. No. SIG-H5253) ELISA bioactivity

Immobilized Human CD47, His Tag (Cat. No. CD7-H5227) at 5 μg/mL (100 μL/well) can bind Human SIRP gamma, Fc Tag (Cat. No. SIG-H5253) with a linear range of 20-312 ng/mL (QC tested).

SIG-H82E3-MALS-HPLC
Biotinylated Human SIRP gamma, His,Avitag (Cat. No. ) MALS images

The purity of Biotinylated Human SIRP gamma, His,Avitag (Cat. No. SIG-H82E3) was more than 90% and the molecular weight of this protein is around 45-57 kDa verified by SEC-MALS.

Bioactivity-ELISA
Biotinylated Human SIRP gamma, His,AvitagBiotinylated Human SIRP gamma, His,Avitag (Cat. No. SIG-H82E3) ELISA bioactivity

Immobilized Biotinylated Human SIRP gamma, His,Avitag (Cat. No. SIG-H82E3) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Human CD47, Mouse IgG2a Fc Tag (Cat. No. CD7-H52A5) with a linear range of 4-31 ng/mL (QC tested).

Synonym Name

SIRPG,CD172g,SIRPB2,SIRP-gamma,SIRP-b2,SIRP-beta-2,Cripto-1

Background

Signal-regulatory protein gamma (SIRPG or SIRP-gamma) is also known as CD172 antigen-like family member B (CD172g), Signal-regulatory protein beta-2 (SIRPB2), is a single-pass type I  membrane protein. SIRPG is expressed on CD4+ T-cells, CD8+ T-cells, CD56-bright natural killer (NK) cells, CD20+ cells, and all activated NK cells. SIRPG interacts with CD47. On binding with CD47, CD172g mediates cell-cell adhesion.

Clinical and Translational Updates

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