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Brief Information

Name:Tumor necrosis factor receptor superfamily member 12A
Target Synonym:FGF-inducible 14,TWEAK Receptor,Tumor Necrosis Factor Receptor Superfamily, Member 12A,CD266 Antigen,FN14,TNF Receptor Superfamily Member 12A,Type I Transmembrane Protein Fn14,TNR12,Tweak-receptor,TweakR,Fibroblast growth factor-inducible immediate-early response protein 14,Tumor necrosis factor receptor superfamily member 12A,CD266,TNFRSF12A
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Pending

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Cat. No. Species Product Description Structure Purity Feature
TNA-H526a Human Human TWEAK R / TNFRSF12A Protein, Fc Tag
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Synonym Name

TNFRSF12A,FGF-inducible 14,FN14,TweakR,CD266


Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A) is also known as Fibroblast growth factor-inducible immediate-early response protein 14 (FN14 or FGF-inducible 14), Tweak-receptor, CD antigen CD266. TNFRSF12A contains one TNFR-Cys repeat. TNFRSF12A is highly expressed in heart, placenta and kidney. TNFRSF12A is receptor for TNFSF12/TWEAK, and is weak inducer of apoptosis in some cell types. TNFRSF12A / FN14 promotes angiogenesis and the proliferation of endothelial cells.

Clinical and Translational Updates

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