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Your Position: Home > uPAR

uPAR

uPAR Protein Product ListCompare or Buy

Product> Filter Results

Cat. No.	Species	Product Description	Structure	Purity	Feature
UPR-H82E7	Human	Biotinylated Human uPAR / PLAUR Protein, His,Avitag™
UPR-H5226	Human	Human uPAR / PLAUR Protein, His Tag

uPAR Part of Bioactivity data

UPR-H5226-ELISA

Measured by its inhibitory ability in a competitive ELISA.
Serial dilutions of Human uPAR, His Tag (Cat. No. UPR-H5226) were added into Human PLAU, His Tag (Cat. No. PLU-H5229) : Biotinylated Human uPAR, His,Avitag (Cat. No. UPR-H82E7) binding reactions. The half maximal inhibitory concentration (IC50) is 2.96 μg/mL (QC tested).

Protocol

UPR-H82E7-ELISA

Immobilized Human PLAU, His Tag (Cat. No. PLU-H5229) at 5 μg/mL (100 μL/well) can bind Biotinylated Human uPAR, His,Avitag (Cat. No. UPR-H82E7) with a linear range of 0.3-2 ng/mL (QC tested).

Protocol

uPAR Molecule Synonym Name

uPAR,PLAUR,CD87,MO3

uPAR Molecule Background

Urokinase plasminogen activator surface receptor (U-PAR) is also known as PLAUR, Monocyte activation antigen Mo3, CD antigen CD87. PLAUR contains three UPAR/Ly6 domains. U-PAR is expressed in neurons of the rolandic area of the brain (at protein level) and is also expressed in the brain. PLAUR / CD87 interacts with MRC2, SRPX2 and SORL1. PLAUR / UPAR acts as a receptor for urokinase plasminogen activator and plays a role in localizing and promoting plasmin formation. U-PAR mediates the proteolysis-independent signal transduction activation effects of U-PA.