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Cat. No. Species Product Description Structure Purity Feature
UPR-H82E7 Human Biotinylated Human uPAR / PLAUR Protein, His,Avitag™
UPR-H5226 Human Human uPAR / PLAUR Protein, His Tag

uPAR Part of Bioactivity data

Human uPAR, His TagHuman uPAR, His Tag (Cat. No. UPR-H5226) ELISA bioactivity

Measured by its inhibitory ability in a competitive ELISA.
Serial dilutions of Human uPAR, His Tag (Cat. No. UPR-H5226) were added into Human PLAU, His Tag (Cat. No. PLU-H5229) : Biotinylated Human uPAR, His,Avitag (Cat. No. UPR-H82E7) binding reactions. The half maximal inhibitory concentration (IC50) is 2.96 μg/mL (QC tested).

Biotinylated Human uPAR, His,AvitagBiotinylated Human uPAR, His,Avitag (Cat. No. UPR-H82E7) ELISA bioactivity

Immobilized Human PLAU, His Tag (Cat. No. PLU-H5229) at 5 μg/mL (100 μL/well) can bind Biotinylated Human uPAR, His,Avitag (Cat. No. UPR-H82E7) with a linear range of 0.3-2 ng/mL (QC tested).

uPAR Molecule Synonym Name


uPAR Molecule Background

Urokinase plasminogen activator surface receptor (U-PAR) is also known as PLAUR, Monocyte activation antigen Mo3, CD antigen CD87. PLAUR contains three UPAR/Ly6 domains. U-PAR is expressed in neurons of the rolandic area of the brain (at protein level) and is also expressed in the brain. PLAUR / CD87 interacts with MRC2, SRPX2 and SORL1. PLAUR / UPAR acts as a receptor for urokinase plasminogen activator and plays a role in localizing and promoting plasmin formation. U-PAR mediates the proteolysis-independent signal transduction activation effects of U-PA.

uPAR References

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