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Your Position: Home > CD117

CD117

Brief Information

Name:Stem cell growth factor receptor
Target Synonym:EC 2.7.10,EC:2.7.10.1,MASTC,KIT Proto-Oncogene Receptor Tyrosine Kinase,V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene-Like Protein,p145 c-kit,SCFR,KIT,Proto-Oncogene C-Kit,Proto-Oncogene Tyrosine-Protein Kinase Kit,Soluble KIT Variant 1,C-Kit Protooncogene,CD117 Antigen,Piebald Trait,EC 2.7.10.1,C-Kit,CD117,Proto-Oncogene Proteins c-kit,Mast/stem cell growth factor receptor Kit,PBT,Piebald trait protein,Tyrosine-protein kinase Kit,KIT Proto-Oncogene, Receptor Tyrosine Kinase,v-kit Hardy-
Number of Launched Drugs:15
Number of Drugs in Clinical Trials:17
Lastest Research Phase:Approved

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Part of Bioactivity data

CD7-H82E6-ELISA
 CD117 ELISA

Immobilized Human SCF protein, His Tag at 2 μg/mL (100 μL/well) can bind Biotinylated Human CD117, His,Avitag (Cat. No. CD7-H82E6) with a linear range of 0.02-0.625 μg/mL (QC tested).

CD7-C52H9-MALS-HPLC
Cynomolgus CD117, His Tag (Cat. No. ) MALS images

The purity of Cynomolgus CD117, His Tag (Cat. No. CD7-C52H9) is more than 90% and the molecular weight of this protein is around 68-88 kDa verified by SEC-MALS.

Bioactivity-ELISA
Cynomolgus CD117, His TagCynomolgus CD117, His Tag (Cat. No. CD7-C52H9) ELISA bioactivity

Immobilized Cynomolgus CD117, His Tag (Cat. No. CD7-C52H9) at 2 μg/mL (100 μL/well) can bind Biotinylated Human SCF, Avitag,His Tag (Cat. No. SCF-H82E1) with a linear range of 0.2-5 ng/mL (QC tested).

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Synonym Name

CD117,SCFR,c-Kit,KIT

Background

Mast/stem cell growth factor receptor Kit (c-Kit), a member of  the protein kinase superfamily, Tyr protein kinase family and CSF-1/PDGF receptor subfamily, is also known as piebald trait protein (PBT), p145 c-kit, tyrosine-protein kinase Kit and CD117,which contains five Ig-like C2-type (immunoglobulin-like) domains and one protein kinase domain. CD117 acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, CD117 can activate several signaling pathways. Furthermore, Activated KIT promotes phosphorylation of the protein phosphatases PTPN6/SHP-1 and PTPRU, and of the transcription factors STAT1, STAT3, STAT5A and STAT5B.

Clinical and Translational Updates

Related Molecule

SCF

Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Sorafenib Tosylate NSC-724772; BAY-43-0006; BAY-43-9006; BAY-54-9085 Approved Onyx Pharmaceuticals Inc Nexavar, 多吉美 EU Thyroid Neoplasms Bayer AG 2005-12-01 Lung Neoplasms; Adrenocortical Carcinoma; Mesothelioma; Breast Neoplasms; Hepatitis B; Prostatic Neoplasms; Brain Neoplasms; Sarcoma; Pulmonary Arterial Hypertension; Medullary thyroid cancer (MTC); Hepatitis C; Thyroid Neoplasms; Leukemia, Monocytic, Acute; Lymphoma, T-Cell; Digestive System Neoplasms; Leukemia, Myeloid, Acute; Glioma; Venous Thrombosis; Facial Neoplasms; Fallopian Tube Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis; Melanoma; Adenocarcinoma; Fasting; Leukemia, Biphenotypic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasms; Ovarian Neoplasms; Hematopoietic stem cell transplantation (HSCT); Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Solid tumours; Kidney Neoplasms; Recurrence; Carcinoma, Renal Cell; Carcinoma; Stomach Neoplasms; Abdominal Neoplasms; Esophageal Neoplasms; Pancreatic Neoplasms; Liver Neoplasms; Neoplasms, Glandular and Epithelial; Kidney Diseases; Myelodysplastic Syndromes; Myeloproliferative Disorders; Thyroid Details
Pazopanib Hydrochloride GSK-786034; GW-786034B; SB-786034; GW-786034 Approved Glaxosmithkline Plc, Novartis Pharma Ag 维全特, Armala, Votrient, Patorma Mainland China Carcinoma, Renal Cell Novartis Pharma Schweiz Ag 2009-10-19 Urogenital Neoplasms; Prostatic Neoplasms; Osteosarcoma; Peritoneal Neoplasms; Gastrointestinal Stromal Tumors; Colorectal Neoplasms; Carcinoma, Small Cell; Leukemia, Myeloid, Acute; Sarcoma, Alveolar Soft Part; Fallopian Tube Neoplasms; Thyroid Neoplasms; Lung Neoplasms; Breast Neoplasms; Glioma; Carcinoma, Non-Small-Cell Lung; Gastrointestinal Neoplasms; Uterine Cervical Neoplasms; Macular Degeneration; Melanoma; Neoplasm Metastasis; Carcinoma, Hepatocellular; Thyroid Cancer, Papillary; Neoplasms, Germ Cell and Embryonal; Neoplasms; Ovarian Neoplasms; Solid tumours; Chondrosarcoma; Epistaxis; Telangiectasia, Hereditary Hemorrhagic; Leiomyosarcoma; Carcinoma, Renal Cell; Hemangiosarcoma; Squamous Cell Carcinoma of Head and Neck; Thoracic Neoplasms; Head and Neck Neoplasms; Small Cell Lung Carcinoma; Glioblastoma; Pancreatic Neoplasms; Dermatofibrosarcoma; Central Nervous System Neoplasms; Lymphedema; Liposarcoma; Adenocarcinoma, Follicular; Soft Tissue Neoplasms; Sarcoma Details
Pexidartinib PLX-3397 Approved Daiichi Sankyo Co Ltd Turalio United States Giant Cell Tumor of Tendon Sheath Daiichi Sankyo Inc 2019-08-02 Giant Cell Tumor of Tendon Sheath; Solid tumours; Synovitis, Pigmented Villonodular; Hodgkin Disease; Glioblastoma; Neoplasms; Giant Cell Tumors; Prostatic Neoplasms; Gastrointestinal Stromal Tumors; Leukemia, Myeloid, Acute; Melanoma Details
Ponatinib Hydrochloride AP24534 hydrochloride; AP24534-HCL; AP24534 HCl; INCB-84344; AP-24534 Approved Ariad Iclusig Japan Precursor Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, Myelogenous, Chronic, BCR-ABL Positive Otsuka Holdings Co Ltd 2012-12-14 Precursor Cell Lymphoblastic Leukemia-Lymphoma; Carcinoma, Non-Small-Cell Lung; Leukemia, Biphenotypic, Acute; Lymphoma; Leukemia, Myeloid, Acute; Leukemia, Myeloid, Chronic-Phase; Gastrointestinal Stromal Tumors; Philadelphia Chromosome; Medullary thyroid cancer (MTC); Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Blast Crisis; Small Cell Lung Carcinoma; Adenocarcinoma of Lung; Solid tumours; Leukemia, Myeloid, Accelerated Phase; Leukemia; Hematologic Neoplasms Details
Ripretinib DCC-2618 Approved Deciphera 擎乐, Qinlock United Kingdom Gastrointestinal Stromal Tumors Deciphera Pharmaceuticals Llc 2020-05-15 Neoplasms; Mastocytosis, Systemic; Gastrointestinal Stromal Tumors Details
Regorafenib DAST; BAY-73-4506 Approved Bayer AG Stivarga, Resihance Mainland China Gastrointestinal Stromal Tumors Bayer Pharma Ag 2012-09-27 Leukemia, Myeloid, Acute; Sarcoma; Gastrinoma; Colorectal Neoplasms; Gastrointestinal Stromal Tumors; Bile Duct Neoplasms; Peritoneal Neoplasms; Lymphoma, Non-Hodgkin; Lung Neoplasms; Carcinoma, Adenoid Cystic; Thyroid Neoplasms; Fallopian Tube Neoplasms; Carcinoma, Hepatocellular; Melanoma; Neoplasm Metastasis; Gastrointestinal Neoplasms; Somatostatinoma; Solid tumours; Glucagonoma; Multiple Myeloma; Pancreatic Neoplasms; Carcinoma, Ovarian Epithelial; Carcinoma, Transitional Cell; Neoplasms; Glioblastoma; Colonic Neoplasms; Hemangiosarcoma; Carcinoma, Islet Cell; Insulinoma; Carcinoid Tumor; Rectal Neoplasms; Carcinoma, Renal Cell; Ovarian Neoplasms Details
Midostaurin PKC-412; PKC-412A; CGP-41231; CGP-41251 Approved Novartis Pharma Ag Rydapt EU Leukemia, Myeloid, Acute; Mastocytosis Novartis Europharm Ltd 2017-04-28 Hematologic Neoplasms; Leukemia; Mastocytosis, Systemic; Myelodysplastic Syndromes; Leukemia, Mast-Cell; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Hepatic Insufficiency; Leukemia, Myeloid, Acute; Mastocytosis Details
Avapritinib BLU-285; CS-3007 Approved Blueprint Medicines Corp Ayvakit, Ayvakyt, 泰吉华 EU Mastocytosis, Systemic Blueprint Medicines (Netherlands) Bv 2020-01-09 Solid tumours; Hematologic Neoplasms; Mastocytosis, Systemic; Central Nervous System Neoplasms; Leukemia, Mast-Cell; Gastrointestinal Stromal Tumors Details
Cabozantinib S-malate XL-184; BMS-907351 Approved Exelixis Inc Cometriq, Cabometyx Japan Carcinoma, Renal Cell Takeda 2012-11-29 Thyroid Neoplasms; Adenocarcinoma, Follicular; Brain Neoplasms; Sarcoma; Neuroblastoma; Neurofibroma, Plexiform; Prostatic Neoplasms; Cholangiocarcinoma; Colorectal Neoplasms; Astrocytoma; Hepatic Insufficiency; Bile Duct Neoplasms; Central Nervous System Neoplasms; Lymphoma; Leukemia, Myeloid, Acute; Glioma; Carcinoma, Neuroendocrine; Carcinoma, Hepatocellular; Neoplasms, Germ Cell and Embryonal; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma; Thyroid Cancer, Papillary; Meningioma; Carcinoma, Transitional Cell; Kidney Neoplasms; Ovarian germ cell tumor; Bone metastases; Carcinoma, Renal Cell; Rejection of liver transplantation; Esophageal Neoplasms; Pain; Stomach Neoplasms; Carcinoma, Merkel Cell; Glioblastoma; Seminoma; Solid tumours; Neurofibromatoses; Neoplasms; Salivary Gland Neoplasms; Carcinoma, Papillary; Skin Neoplasms; Kidney Diseases; Neuroendocrine Tumors; Adrenocortical Carcinoma; Prostatic Neoplasms, Castration-Resistant; Multiple Myeloma Details
Olverembatinib D-824; GZD-824; APG-1351; GIBH-824; HQP-1351 Approved Guangzhou Institute Of Biomedicine And Health, Chinese Academy Of Sciences 耐立克 Mainland China Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Accelerated Phase Guangzhou Shunjian Biomedical Technology Co Ltd 2021-11-25 Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Accelerated Phase; Leukemia; Leukemia, Myeloid; Solid tumours; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Gastrointestinal Stromal Tumors Details
Imatinib mesylate CGP-57148B; CGP-57148; STI-571; QTI-571; CTI-571; VR325; AER-901; YD-312; TNX-201 Approved Novartis Pharma Ag glivic, 格列卫, Gleevec, Ruvise, Glivec, Gleevec/Glivec United States Precursor Cell Lymphoblastic Leukemia-Lymphoma Novartis Pharma Ag 2001-05-10 Leukemia, Myeloid, Acute; Pulmonary Fibrosis; Respiratory Distress Syndrome, Adult; Prostatic Neoplasms; Pulmonary Arterial Hypertension; Neurofibrosarcoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Neurofibroma, Plexiform; Sarcoma; Leukemia, Myeloid, Chronic-Phase; Gastrointestinal Stromal Tumors; Philadelphia Chromosome; Primary Myelofibrosis; Colorectal Neoplasms; Urogenital Neoplasms; Lymphangioleiomyomatosis; Nephrogenic Fibrosing Dermopathy; Thymoma; Lymphoma, T-Cell; Thyroid Neoplasms; Scleroderma, Localized; Pulmonary Edema; Prostatic Diseases; Acute Lung Injury; Myelodysplastic-Myeloproliferative Diseases; Neoplasm Metastasis; Melanoma; Fibroma; Anemia, Sickle Cell; Glioblastoma; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Hypereosinophilic Syndrome; Leukemia; Head and Neck Neoplasms; Neoplasm, Residual; Hematopoietic stem cell transplantation (HSCT); Diabetes Mellitus, Type 1; Hypertension, Pulmonary; Abdominal Neoplasms; Genital Neoplasms, Male; Rhinitis, Allergic, Seasonal; Mastocytosi Details
Lenvatinib Mesylate ER-203492-00; E-7080; MK-7902 Approved Eisai Co Ltd Lenvima, Lenvima/Kisplyx, 乐卫玛, Kisplyx Japan Carcinoma, Renal Cell Merck Sharp & Dohme Corp 2015-02-13 Carcinoma, Adenoid Cystic; Thrombosis; Thyroid Cancer, Papillary; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular; Melanoma; Esophageal Squamous Cell Carcinoma; Endometrial Neoplasms; Lymphoma; Thyroid Neoplasms; Colorectal Neoplasms; Hepatic Insufficiency; Cholangiocarcinoma; Breast Neoplasms; Sarcoma; Neuroendocrine Tumors; Solid tumours; Urinary Bladder Neoplasms; Adenocarcinoma, Follicular; Liver Diseases; Small Cell Lung Carcinoma; Neoplasms; Kidney Diseases; Thyroid Carcinoma, Anaplastic; Adenocarcinoma of Lung; Rejection of liver transplantation; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Renal Insufficiency; Carcinoma, Renal Cell; Liver Neoplasms; Biliary Tract Neoplasms Details
Anlotinib Dihydrochloride AL-3818 Approved Advenchen Laboratories, Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd 福可维 Mainland China Thyroid Neoplasms Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd 2018-05-08 Thyroid Neoplasms; Nasopharyngeal Carcinoma; Lymphoma, Extranodal NK-T-Cell; Cholangiocarcinoma; Bile Duct Diseases; Bone Neoplasms; Colorectal Neoplasms; Peritoneal Neoplasms; Gastrointestinal Stromal Tumors; Urologic Neoplasms; Sarcoma, Alveolar Soft Part; Endometrial Neoplasms; Gallbladder Neoplasms; Esophageal Squamous Cell Carcinoma; Medullary thyroid cancer (MTC); Carcinoma, Squamous Cell; Fallopian Tube Neoplasms; Glioma; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms; Melanoma; Carcinoma, Hepatocellular; Esophageal Diseases; Paraganglioma; Adenocarcinoma; Osteoma; Gastrointestinal Neoplasms; Squamous Cell Carcinoma of Head and Neck; Leiomyosarcoma; Head and Neck Neoplasms; Biliary Tract Neoplasms; Solid tumours; Chondrosarcoma; Liver Neoplasms; Esophageal Neoplasms; Thoracic Neoplasms; Genital Diseases, Female; Stomach Neoplasms; Pheochromocytoma; Digestive System Diseases; Gastrointestinal Diseases; Ovarian Neoplasms; Carcinoma, Renal Cell; Small Cell Lung Carcinoma; Tripl Details
Dasatinib Hydrate BMS-354825; NSC-732517 Approved Bristol-Myers Squibb Company 施达赛, Spricel, Sprycel, Spraysel Mainland China Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Precursor Cell Lymphoblastic Leukemia-Lymphoma Bristol-Myers Squibb Pharma Eeig 2006-06-28 Leukemia, Myeloid, Acute; Prostatic Neoplasms; Cholangiocarcinoma; Sarcoma; Neurofibrosarcoma; Sarcoma, Ewing; Leukemia, Myeloid, Chronic-Phase; Alzheimer Disease; Cognitive Dysfunction; Primary Myelofibrosis; Giant Cell Tumor of Bone; Gastrointestinal Stromal Tumors; Lymphoma, Non-Hodgkin; Breast Neoplasms; Lung Neoplasms; Waldenstrom Macroglobulinemia; Sarcoma, Alveolar Soft Part; Lymphoma; Hemangiopericytoma; Endometrial Neoplasms; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung; Leukemia, Lymphocytic, Chronic, B-Cell; Melanoma; Mastocytosis; Myelodysplastic Syndromes; Leukemia, Myeloid, Accelerated Phase; Solid tumours; Leukemia; Leukemia, Myeloid; Hypereosinophilic Syndrome; Rhabdomyosarcoma; Chondrosarcoma; Polycythemia Vera; Leukemia, Lymphoid; Neoplasms; Idiopathic Pulmonary Fibrosis; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mastocytosis, Systemic; Scleroderma, Systemic; Triple Negative Breast Neoplasms; Leukemia, Myelomonocytic, Chronic; Coronavirus Disease 2019 (COVID-19); Lymphoma, Lar Details
Sunitinib Malate PHA-290940; SU-010398; SU-11248; PNU-290940AD; PHA-290940AD; GB-102; PNU-290940; SU-011248-L-malate salt Approved Pfizer Pharmaceuticals Ltd (China) 索坦, Sutent Japan Pancreatic neuroendocrine tumors (pNET) Pfizer Inc 2006-01-26 Diabetic macular oedema; Thyroid Neoplasms; Lung Neoplasms; Lymphoma, Non-Hodgkin; Peritoneal Neoplasms; Astrocytoma; Thymus Neoplasms; Urologic Neoplasms; Colorectal Neoplasms; Gastrointestinal Stromal Tumors; Thymoma; Neurofibroma, Plexiform; Cholangiocarcinoma; Medullary thyroid cancer (MTC); Brain Neoplasms; Urethral Neoplasms; Prostatic Neoplasms; Sarcoma; Breast Neoplasms; Adrenocortical Carcinoma; Adenocarcinoma; Paraganglioma; Melanoma; Thyroid Cancer, Papillary; Retinal Vein Occlusion; Meningioma; von Hippel-Lindau Disease; Neoplasm Metastasis; Macular Degeneration; Carcinoma, Hepatocellular; Adenocarcinoma, Follicular; Carcinoma, Non-Small-Cell Lung; Fallopian Tube Neoplasms; Neoplasms, Gonadal Tissue; Nervous System Neoplasms; Germinoma; Brain metastases; Hemangiopericytoma; Urogenital Neoplasms; Hemangioblastoma; Glioblastoma; Pheochromocytoma; Pelvic Neoplasms; Thoracic Neoplasms; Esophageal Neoplasms; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Carcinoma, Islet Cell; Histiocytom Details

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
GS-0174 GS-0174 Phase 1 Clinical Forty Seven Hematologic Neoplasms Details
18F-Dasatinib 18F-SKI-249380; [18F]-Fluoro-BMS-354825; [18F]Dasatinib; [18F]SKI-249380; [18F]Fluoro-BMS-354825 Phase 1 Clinical Memorial Sloan Kettering Cancer Center Neoplasms; Diagnostic agents Details
Sorafenib Tosylate/MG-K10 MG-D-1609 Phase 2 Clinical Metagone Biotech Solid tumours Details
THB-001 THB-001 Phase 1 Clinical Novartis Corp Gastrointestinal Diseases; Chronic Urticaria; Respiratory Tract Diseases Details
AGX-0073 AGX-0073 Phase 1 Clinical Shanghai Aojian Biological Technology Co Ltd Solid tumours Details
Motesanib Diphosphate AMG-706 Amgen Inc Details
Anti-c-kit humanised IgG1/κ antibody-maitansine conjugate (Novartis) LOP-628 Novartis Pharma Ag Details
CDX-0158 CDX-0158; KTN-0158 Yale University, University Of Toronto - St. George Campus Details
T-1301 T-1301; DBPR-216 Taivex Therapeutics Corp Details
THE-630 THE-630 Phase 1 Clinical Theseus Pharmaceuticals Inc Gastrointestinal Stromal Tumors Details
Vatalanib succinate ZK-222584; CGP-79787D; PTK-787 Novartis Pharma Ag Details
Subutinib Maleate Phase 1 Clinical China State Institute Of Pharmaceutical Industry, Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd Solid tumours; Neoplasms Details
SU-014813 SU-14813; SU-014813 Pfizer Pharmaceuticals Ltd (China) Details
Bezuclastinib PLX-9486; CGT-9486 Daiichi Sankyo Co Ltd Details
Telatinib EOC-315; BAY-57-9352 Phase 2 Clinical Bayer AG Solid tumours; Stomach Neoplasms Details
AKN-028 BVT-II; AKN-028; BVT-63628 Akinion Details
XL-820 XL-820 Exelixis Details
Imatinib dry powder inhalation (Aerovate Therapeutics) AV-101(Aerovate Therapeutics) Phase 3 Clinical Pulmonary Arterial Hypertension Details
Sorafenib/MG-005 MGD-1509; MG-D-1509 Metagone Biotech, Tri-Service General Hospital Details
MGTA-117 MGTA-117 Phase 2 Clinical Heidelberg, Magenta Therapeutics Inc Myelodysplastic Syndromes; Leukemia, Myeloid, Acute Details
QBH-196 QBH-196 Phase 1 Clinical Shenyang Pharmaceutical University Solid tumours; Stomach Neoplasms Details
Tafetinib Malate SIM-0702; SIM-1005; SIM-010603 Phase 1 Clinical Jiangsu Simcere Pharmaceutical Co Ltd, Nanjing Yoko Biomedical Co Ltd, Jilin Boda Pharmaceutical Co Ltd Neoplasms Details
Briquilimab JSP-191; AMG-191 Phase 2 Clinical Amgen Inc Myelodysplastic Syndromes; Severe Combined Immunodeficiency; Leukemia, Myeloid, Acute Details
NMS-03592088 NMS-P088; NMS-03592088 Phase 2 Clinical Nerviano Medical Sciences Leukemia, Myelomonocytic, Chronic; Leukemia, Myeloid, Acute Details
Chiauranib CS-2164 Phase 3 Clinical Shenzhen Chipscreen Biosciences Co Ltd Ovarian Neoplasms; Solid tumours; Small Cell Lung Carcinoma; Triple Negative Breast Neoplasms; Neoplasms; Sarcoma; Lymphoma, Non-Hodgkin; Carcinoma, Hepatocellular Details
Barzolvolimab CDX-0159 Phase 2 Clinical Yale University, University Of Toronto - St. George Campus Chronic Urticaria; Skin Diseases; Prurigo; Urticaria Details

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