| Cat. No. | Species | Product Description | Structure | Purity | Feature |
|---|---|---|---|---|---|
| CD7-H82E6 | Human | Biotinylated Human CD117 / c-kit Protein, His,Avitag (MALS verified) |  |
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| CD7-R5259 | Rhesus macaque | Rhesus macaque CD117 / c-kit Protein, Fc Tag (MALS verified) |  |
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| CD7-M5259 | Mouse | Mouse CD117 / c-kit Protein, Fc Tag |  |
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| CD7-H5255 | Human | Human CD117 / c-kit Protein, Fc Tag (MALS verified) |  |
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| CD7-H52H4 | Human | Human CD117 / c-kit Protein, His Tag (MALS verified) |  |
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Immobilized Rhesus macaque CD117, Fc Tag (Cat. No. CD7-R5259) at 2 μg/mL (100 μL/well) can bind ActiveMax® Human SCF, His Tag (Cat. No. SCF-H4219) with a linear range of 0.2-2 ng/mL (QC tested).
The purity of Biotinylated Human CD117, His,Avitag (Cat. No. CD7-H82E6) is more than 90% and the molecular weight of this protein is around 74-100 kDa verified by SEC-MALS.
| Name | Research Code | Research Phase | Company | First Brand Name | First Approved Country | First Indication | First Approved Company | First Approved Date | Indications | Clinical Trials |
|---|---|---|---|---|---|---|---|---|---|---|
| Ancestim | AMJ-9302 | Approved | Amgen Inc | Stemgen | Hematopoietic stem cell transplantation (HSCT) | Details | ||||
| Midostaurin | PKC-412; PKC-412A; CGP-41231; CGP-41251 | Approved | Novartis Pharma Ag | Rydapt | EU | Leukemia, Myeloid, Acute; Mastocytosis | Novartis Europharm Ltd | 2017-04-28 | Hematologic Neoplasms; Leukemia; Mastocytosis, Systemic; Leukemia, Mast-Cell; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Hepatic Insufficiency; Leukemia, Myeloid, Acute; Mastocytosis | Details |
| Pexidartinib | PLX-3397 | Approved | Daiichi Sankyo Co Ltd | Turalio | United States | Giant Cell Tumor of Tendon Sheath | Daiichi Sankyo Inc | 2019-08-02 | Giant Cell Tumor of Tendon Sheath; Solid tumours; Synovitis, Pigmented Villonodular; Hodgkin Disease; Arthritis, Rheumatoid; Glioblastoma; Giant Cell Tumors; Prostatic Neoplasms; Gastrointestinal Stromal Tumors; Leukemia, Myeloid, Acute | Details |
| Sorafenib Tosylate | NSC-724772; BAY-43-0006; BAY-43-9006; BAY-54-9085 | Approved | Onyx Pharmaceuticals Inc | 多吉美, Nexavar | EU | Thyroid Neoplasms | Bayer Ag | 2005-12-01 | Liver Diseases; Neoplasm Metastasis; Fasting; Melanoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Lung Neoplasms; Thyroid Neoplasms; Hepatitis C; Hepatitis B; Breast Neoplasms; Liver Neoplasms; Neoplasms; Pancreatic Neoplasms; Kidney Diseases; Carcinoma; Carcinoma, Renal Cell; Kidney Neoplasms; Solid tumours; Ovarian Neoplasms; Leukemia, Myelogenous, Chronic, BCR-ABL Positive | Details |
| Ripretinib | DCC-2618 | Approved | Deciphera | Qinlock, 擎乐 | Mainland China | Gastrointestinal Stromal Tumors | Zai Lab (Shanghai) Co Ltd | 2020-05-15 | Mastocytosis, Systemic; Gastrointestinal Stromal Tumors | Details |
| Pazopanib Hydrochloride | GW-786034; SB-786034; GSK-786034; GW-786034B | Approved | Glaxosmithkline Plc, Novartis Pharma Ag | 维全特, Armala, Patorma, Votrient | Mainland China | Carcinoma, Renal Cell | Novartis Pharma Schweiz Ag | 2009-10-19 | Osteosarcoma; Macular Degeneration; Carcinoma, Non-Small-Cell Lung; Melanoma; Carcinoma, Hepatocellular; Fallopian Tube Neoplasms; Glioma; Peritoneal Neoplasms; Colorectal Neoplasms; Prostatic Neoplasms; Ovarian Neoplasms; Breast Neoplasms; Sarcoma; Pancreatic Neoplasms; Small Cell Lung Carcinoma; Hemangiosarcoma; Carcinoma, Renal Cell; Solid tumours; Chondrosarcoma; Telangiectasia, Hereditary Hemorrhagic | Details |
| Regorafenib Monohydrate | BAY-73-4506; DAST | Approved | Bayer Ag | Stivarga, Resihance | Mainland China | Gastrointestinal Stromal Tumors | Bayer Pharma Ag | 2012-09-27 | Solid tumours; Rectal Neoplasms; Carcinoma, Renal Cell; Colonic Neoplasms; Colorectal Neoplasms; Gastrointestinal Stromal Tumors; Carcinoma, Hepatocellular; Gastrointestinal Neoplasms | Details |
| Anlotinib Dihydrochloride | AL-3818 | Approved | Advenchen Laboratories, Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd | 福可维 | Mainland China | Small Cell Lung Carcinoma | Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd | 2018-05-08 | Esophageal Squamous Cell Carcinoma; Nasopharyngeal Carcinoma; Gastrointestinal Stromal Tumors; Bone Neoplasms; Peritoneal Neoplasms; Colorectal Neoplasms; Endometrial Neoplasms; Thyroid Neoplasms; Sarcoma, Alveolar Soft Part; Cholangiocarcinoma; Lung Neoplasms; Fallopian Tube Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular; Melanoma; Adenocarcinoma; Osteoma; Triple Negative Breast Neoplasms; Solid tumours; Ovarian Neoplasms; Leiomyosarcoma; Liver Neoplasms; Genital Diseases, Female; Carcinoma, Renal Cell; Stomach Neoplasms; Esophageal Neoplasms; Biliary Tract Neoplasms; Small Cell Lung Carcinoma; Lymphoma, Large B-Cell, Diffuse; Carcinoma, Ovarian Epithelial; Sarcoma, Synovial; Neuroendocrine Tumors; Medullary thyroid cancer (MTC); Sarcoma | Details |
| Ponatinib Hydrochloride | AP-24534; INCB-84344; AP24534 HCl; AP24534-HCL; AP24534 hydrochloride | Approved | Ariad | Iclusig | Japan | Precursor Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, Myelogenous, Chronic, BCR-ABL Positive | Otsuka Holdings Co Ltd | 2012-12-14 | Leukemia; Leukemia, Myeloid, Accelerated Phase; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Solid tumours; Hematologic Neoplasms; Blast Crisis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, Myeloid, Chronic-Phase; Philadelphia Chromosome; Gastrointestinal Stromal Tumors; Leukemia, Myeloid, Acute; Lymphoma; Leukemia, Biphenotypic, Acute | Details |
| Avapritinib | BLU-285; CS-3007 | Approved | Blueprint Medicines Corp | Ayvakit, Ayvakyt, 泰吉华 | United States | Leukemia, Mast-Cell; Mastocytosis, Systemic | Blueprint Medicines | 2020-01-09 | Hematologic Neoplasms; Solid tumours; Mastocytosis, Systemic; Leukemia, Mast-Cell; Central Nervous System Neoplasms; Gastrointestinal Stromal Tumors | Details |
| Lenvatinib Mesylate | ER-203492-00; E-7080 | Approved | Eisai Co Ltd | Kisplyx, Lenvima, Lenvima/Kisplyx, ��卫玛 | United States | Endometrial Neoplasms | Eisai Inc | 2015-02-13 | Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Melanoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular; Gallbladder Neoplasms; Lymphoma; Endometrial Neoplasms; Thyroid Neoplasms; Hepatic Insufficiency; Cholangiocarcinoma; Sarcoma; Liver Diseases; Liver Neoplasms; Triple Negative Breast Neoplasms; Kidney Diseases; Small Cell Lung Carcinoma; Thyroid Carcinoma, Anaplastic; Adenocarcinoma of Lung; Esophageal Neoplasms; Renal Insufficiency; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Renal Cell; Biliary Tract Neoplasms; Solid tumours | Details |
| Imatinib mesylate | CGP-57148B; CGP-57148; STI-571; QTI-571; CTI-571; AER-901; VR325 | Approved | Novartis Pharma Ag | glivic, 格列卫, Gleevec, Ruvise, Glivec, Gleevec/Glivec | United States | Precursor Cell Lymphoblastic Leukemia-Lymphoma | Novartis Pharma Ag | 2001-05-10 | Chordoma; Prostatic Diseases; Myelodysplastic-Myeloproliferative Diseases; Acute Lung Injury; Leukemia, Myeloid, Acute; Pulmonary Edema; Urogenital Neoplasms; Philadelphia Chromosome; Gastrointestinal Stromal Tumors; Leukemia, Myeloid, Chronic-Phase; Neurofibrosarcoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Pulmonary Arterial Hypertension; Respiratory Distress Syndrome, Adult; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Chronic eosinophilic leukemia (CEL); Coronavirus Disease 2019 (COVID-19); Leukemia, Myelomonocytic, Chronic; Glioblastoma; Dermatofibrosarcoma; Mastocytosis, Systemic; Myelodysplastic Syndromes; Rhinitis, Allergic, Seasonal; Genital Neoplasms, Male; Abdominal Neoplasms; Leukemia; Genital Diseases, Male; Hypereosinophilic Syndrome | Details |
| Cabozantinib S-malate | BMS-907351; XL-184 | Approved | Exelixis Inc | Cometriq, Cabometyx | Japan | Carcinoma, Renal Cell | Takeda | 2012-11-29 | Solid tumours; Pain; Stomach Neoplasms; Carcinoma, Renal Cell; Esophageal Neoplasms; Glioblastoma; Kidney Diseases; Prostatic Neoplasms; Colorectal Neoplasms; Astrocytoma; Hepatic Insufficiency; Thyroid Neoplasms; Carcinoma, Neuroendocrine; Lymphoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular | Details |
| Dasatinib Hydrate | BMS-354825; NSC-732517 | Approved | Bristol-Myers Squibb Company | 施达赛, Spricel, Sprycel, Spraysel | Mainland China | Precursor Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, Myelogenous, Chronic, BCR-ABL Positive | Bristol-Myers Squibb Pharma Eeig | 2006-06-28 | Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia; Leukemia, Myeloid, Accelerated Phase; Leukemia, Myeloid; Leukemia, Lymphoid; Myelodysplastic Syndromes; Scleroderma, Systemic; Blast Crisis; Prostatic Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Breast Neoplasms; Leukemia, Myeloid, Chronic-Phase; Leukemia, Myeloid, Acute; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung | Details |
| Sunitinib Malate | PHA-290940; SU-010398; SU-11248; GB-102; PNU-290940; SU-011248-L-malate salt; PNU-290940AD; PHA-290940AD | Approved | Pfizer Pharmaceuticals Ltd (China) | Sutent, 索坦 | Japan | Pancreatic neuroendocrine tumors (pNET) | Pfizer Inc | 2006-01-26 | Diabetic macular oedema; Macular Degeneration; Carcinoma, Non-Small-Cell Lung; Retinal Vein Occlusion; Carcinoma, Hepatocellular; Urogenital Neoplasms; Urologic Neoplasms; Colorectal Neoplasms; Gastrointestinal Stromal Tumors; Prostatic Neoplasms; Breast Neoplasms; Kidney Neoplasms; Neuroendocrine Tumors; Urologic Diseases; Kidney Diseases; Pancreatic neuroendocrine tumors (pNET); Pancreatic Neoplasms; Carcinoma, Islet Cell; Stomach Neoplasms; Carcinoma, Renal Cell; Solid tumours; Liver Neoplasms | Details |
| Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
|---|---|---|---|---|---|
| Imatinib mesylate (YD Global Life Science) | YD-312 | Phase 2 Clinical | Yd Global Life Science | Diabetic macular oedema | Details |
| Hydroxychloroquine/Sorafenib | Phase 1 Clinical | Vg Life Sciences | Ovarian Neoplasms | Details | |
| NMS-03592088 | NMS-P088; NMS-03592088 | Phase 2 Clinical | Nerviano Medical Sciences | Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myelomonocytic, Chronic; Leukemia, Myeloid, Acute | Details |
| Telatinib | EOC-315; BAY-57-9352 | Phase 2 Clinical | Bayer Ag | Solid tumours; Stomach Neoplasms | Details |
| Tafetinib Malate | SIM-0702; SIM-1005; SIM-010603 | Phase 1 Clinical | Jiangsu Xiansheng Pharmaceutical Co Ltd, Nanjing Yoko Biomedical Co Ltd, Jilin Boda Pharmaceutical Co Ltd | Solid tumours; Neoplasms | Details |
| PLX-9486 | PLX-9486 | Phase 2 Clinical | Daiichi Sankyo Co Ltd | Gastrointestinal Stromal Tumors | Details |
| Sorafenib/MG-005 | MGD-1509 | Phase 1 Clinical | Metagone Biotech, Tri-Service General Hospital | Solid tumours | Details |
| JSP-191 | AMG-191; JSP-191 | Phase 2 Clinical | Amgen Inc | Severe Combined Immunodeficiency; Inflammation | Details |
| Dovitinib | TKI-258; CHIR-258; GFKI-258; CHIR-258LC; NVP-TKI258 | Phase 2 Clinical | Novartis Pharma Ag | Carcinoma, Adenoid Cystic; Carcinoma, Endometrioid; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular; Melanoma; Leukemia, Myeloid, Acute; Thyroid Neoplasms; Endometrial Neoplasms; Colorectal Neoplasms; Gastrointestinal Stromal Tumors; Hepatic Insufficiency; Prostatic Neoplasms; Breast Neoplasms; Solid tumours; Adrenocortical Carcinoma; Multiple Myeloma; Pancreatic Neoplasms; Glioblastoma; Adenocarcinoma, Scirrhous; Carcinoma; Carcinoma, Renal Cell; Stomach Neoplasms; Liver Neoplasms; Linitis Plastica; Stomach Diseases | Details |
| KTN-0158 | CDX-0159; KTN-0158 | Phase 1 Clinical | Yale University, University Of Toronto - St. George Campus | Neurofibromatoses; Chronic Urticaria; Neoplasms; Skin Diseases; Urticaria; Inflammation | Details |
| QBH-196 | QBH-196 | Phase 1 Clinical | Shenyang Pharmaceutical University | Stomach Neoplasms | Details |
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