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Your Position: Home > CD52

CD52

CD52 Molecule Information

Name:CAMPATH-1 antigen
Target Synonym:CD52 Antigen (CAMPATH-1 Antigen),Epididymal Secretory Protein E5,He5,CDW52 Antigen (CAMPATH-1 Antigen),CD52 Antigen,HEL-S-171mP,EDDM5,CD52,CDw52,Cambridge pathology 1 antigen,Human epididymis-specific protein 5,CAMPATH-1 antigen,CD52 Molecule,Epididymis S

Number of Launched Drugs:1
Number of Drugs in Clinical Trials:2
Lastest Research Phase:Approved

CD52 Protein Product ListCompare or Buy

Product> Filter Results

Cat. No.	Species	Product Description
CD2-H82E8	Human	Biotinylated Human CD52 Protein, His,Avitag™
CD2-H525a	Human	Human CD52 Protein, Fc Tag
CD2-H82F3	Human	Biotinylated Human CD52 Protein, Fc,Avitag™

CD52 Part of Bioactivity data

CD2-H82E8-SPR

Anti-Human CD52 MAb (Human IgG1) captured on CM5 chip via anti-human IgG Fc antibodies surface can bind Biotinylated Human CD52, His,Avitag (Cat. No. CD2-H82E8) with an affinity constant of 71.8 nM as determined in a SPR assay (Biacore T200) (Routinely tested).

Protocol

CD2-H82E8-BLI

Loaded Biotinylated Human CD52, His,Avitag (Cat. No. CD2-H82E8) on SA Biosensor, can bind Anti-Human CD52 MAb (Human IgG1) with an affinity constant of 137 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

Protocol

CD52 Molecule Synonym Name

CDW52,HE5,CD52,CAMPATH-1 antigen

CD52 Molecule Background

CAMPATH-1 antigen, also known as cluster of differentiation 52 (CD52), is a glycoprotein that in humans is encoded by the CD52 gene.It is widely expressed on the cell surface of immune cells, such as mature lymphocytes, natural killer cells (NK), eosinophils, neutrophils, monocytes/macrophages, and dendritic cells (DCs).ligation of cell surface CD52 molecules may offer costimulatory signals for T-cell activation and proliferation.

CD52 References

CD52 Public Drug Information

Name	Research Code	Research Phase	Company	First Brand Name	First Approved Country	First Indication	First Approved Company	First Approved Date	Indications	Clinical Trials
Alemtuzumab	LDP-03; GZ-402673	Approved	Genzyme Corp, Bayer Ag	Campath, Lemtrada, MabCampath	United States	Multiple Sclerosis	s:12:"Genzyme Corp";	2001-05-07	Hematologic Neoplasms; Graft vs Host Disease; Multiple Sclerosis; Lymphoma, Non-Hodgkin; Leukemia, Lymphocytic, Chronic, B-Cell	Details

CD52 Clinical Drug Information

Name	Research Code	Research Phase	Company	Indications	Clinical Trials
Recombinant anti-CD52 humanized monoclonal antibody (Lanzhou Institute Of Biological Products/Shanghai Taiyin Biotechnology)		Phase 1 Clinical	Lanzhou Institute Of Biological Products Co Ltd, Shanghai Taiyin Biotechnology Co Ltd	Leukemia, B-Cell; Leukemia, Prolymphocytic, T-Cell; Lymphoma; Lymphoma, Non-Hodgkin; Leukemia, Prolymphocytic; Leukemia, Lymphocytic, Chronic, B-Cell	Details
Alemtuzumab biosimilar (Zhangjiang Biotechnology)		Phase 2 Clinical	Shanghai Zhangjiang Biotechnology Co Ltd	Leukemia, Lymphocytic, Chronic, B-Cell	Details
ALLO-647	ALLO-647	Phase 2 Clinical	Allogene Therapeutics	Lymphoma, B-Cell; Carcinoma, Renal Cell; Multiple Myeloma; Lymphoma, Follicular; Lymphoma, Non-Hodgkin	Details