PD-1 & PD-L1 Protein - ACROBiosystems

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PD-1 & PD-L1


EP-101	Human	PD-1 [Biotinylated] : PD-L1 Inhibitor Screening ELISA Assay Pair

Cat. No.

Species

Product Description

Structure

Purity

Feature

EP-101

Human

PD-1 [Biotinylated] : PD-L1 Inhibitor Screening ELISA Assay Pair

Part of Bioactivity data

EP-101-BLI

PD-1 [Biotinylated] : PD-L1 Inhibitor Screening ELISA Assay Pair
PD-1 [Biotinylated] : PD-L1 Inhibitor Screening ELISA Assay Pair
(Cat. No. EP-101) ELISA bioactivity

BINDING OF BIOTINYLATED HUMAN PD-1 TO IMMOBILIZED HUMAN PD-L1 IN A FUNCTIONAL ELISA ASSAY.
Immobilized human PD-L1 protein at 2 μg/mL (100 μL/well) can bind human PD-1-Biotin with a linear range of 0.01-0.2 μg/mL when detected by Streptavidin-HRP. Background was subtracted from data points before curve fitting. (QC tested)

Protocol

PD-1 & PD-L1 Molecule Synonym Name

PD-1 & PD-L1

PD-1 & PD-L1 Molecule Background

Immune checkpoint pathway is a focal point of today’s cancer research. PD-1 is one of the best characterized checkpoint proteins. The binding between PD-1 and its ligand PD-L1 suppresses T-cell activation and allows cancer cells to escape from body’s immune surveillance. Therefore, the pharmaceutical inhibition of PD-1 or its ligand has been considered a promising strategy by many oncologists.

PD-1 & PD-L1 References

Related Molecule