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Your Position: Home > PD-1 & PD-L1

PD-1 & PD-L1

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Cat. No. Species Product Description Structure Purity Feature
EP-101 Human PD-1 [Biotinylated] : PD-L1 Inhibitor Screening ELISA Kit
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Part of Bioactivity data

EP-101-BLI
PD-1 & PD-L1 ELISA

INHIBITION OF PD-1-PD-L1 BINDING BY ANTI-PD-1 NEUTRALIZING ANTIBODY (CATALOG # EP101-C03) MEASURED USING THE PD-1 [BIOTINYLATED] : PD-L1 INHIBITOR SCREENING ELISA ASSAY PAIR (CATALOG # EP-101).
Anti-PD-1 neutralizing antibody was diluted from 10 μg/mL to 0.078 μg/ mL (69.628 nM to 0.544 nM) and loaded onto the plate coated by human PD-L1 in the presence of human PD-1-Biotin. Assay was performed according to the protocol in PD-1[Biotinylated] : PD-L1 Inhibitor Screening ELISA Assay Pair. Background was subtracted from data points prior to log transformation and curve fitting (QC tested).

Protocol

PD-1 & PD-L1 Molecule Synonym Name

PD-1 & PD-L1

PD-1 & PD-L1 Molecule Background

Immune checkpoint pathway is a focal point of today’s cancer research. PD-1 is one of the best characterized checkpoint proteins. The binding between PD-1 and its ligand PD-L1 suppresses T-cell activation and allows cancer cells to escape from body’s immune surveillance. Therefore, the pharmaceutical inhibition of PD-1 or its ligand has been considered a promising strategy by many oncologists.

PD-1 & PD-L1 References

Related Molecule

PD-L1

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