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Your Position: Home > Integrin alpha V beta 3

Integrin alpha V beta 3

Integrin alpha V beta 3 Protein Product ListCompare or Buy

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Cat. No.	Species	Product Description	Structure	Purity	Feature
IT3-H52E3	Human	Human Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein, His Tag&Tag Free

Integrin alpha V beta 3 Part of Bioactivity data

IT3-H52E3-ELISA

Immobilized Human Fibronectin at 2 μg/mL (100 μL/well) can bind Human ITGAV&ITGB3 Heterodimer Protein, His Tag&Tag Free (Cat. No. IT3-H52E3) with a linear range of 0.01-0.313 μg/mL (QC tested).

Protocol

Integrin alpha V beta 3 Molecule Synonym Name

Integrin alpha V beta 3,ITGAV&ITGB3,ITGAV&B3

Integrin alpha V beta 3 Molecule Background

Integrin alpha-V/beta-3 (ITGAV:ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Also, Integrin alpha-V/beta-3 acts as a receptor for herpes virus 8/HHV-8, coxsackievirus A9, Hantaan virus, cytomegalovirus/HHV-5, human metapneumovirus, human parechovirus 1 and west nile virus. Furthermore, in case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.