0
There is no goods in the shopping cart !
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Home > Nectin-3

Nectin-3

Nectin-3 Protein Product ListCompare or Buy

Cat. No. Species Product Description Structure Purity Feature
PV3-H82F3 Human Biotinylated Human Nectin-3 / CD113 Protein, Fc Tag, Avi Tag (Avitag™)
PV3-H82F3-structure
PV3-H82F3-sds
PV3-H82F3-elisa_1
PV3-H5255 Human Human Nectin-3 / CD113 Protein, Fc Tag
PV3-H5255-structure
PV3-H5255-sds
PV3-H5255-elisa_1
PV3-H52E4 Human Human Nectin-3 / CD113 Protein
PV3-H52E4-structure
PV3-H52E4-sds

Nectin-3 Molecule Synonym Name

CD113,Nectin-3,PVRL3

Nectin-3 Molecule Background

Poliovirus receptor-related 3 (PVRL3), also known as nectin-3 and CD113, is a human protein of the immunoglobulin superfamily which forms part of adherens junctions. Nectins are immunoglobulin-like adhesion molecules that interact with afadin (AF6; MIM 159559). Afadin is an actin filament-binding protein that connects nectins to the actin cytoskeleton. The nectin-afadin system organizes adherens junctions cooperatively with the cadherin system in epithelial cells. PVRL3 plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with PVRL2/nectin-2 at Sertoli-spermatid junctions. Furthermore, PVRL3 induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation.

Nectin-3 References

Nectin-3 Related Molecule

This web search service is supported by Google Inc.

totop