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Transferrin R2

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Cat. No. Species Product Description Structure Purity Feature
TF2-M5269 Mouse Mouse Transferrin R2 Protein, mouse IgG1 Fc Tag, low endotoxin

Synonym Name

Transferrin R2,TFR2


Transferrin receptor protein 2 (TFR2) is a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. The mutations in TFR2 gene have been associated with hereditary hemochromatosis type III. Furthermore, TFR2 is involved in the uptake of transferrin-bound iron into cells by endocytosis, although its role is minor compared to transferrin receptor 1.

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