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Integrin alpha 6 beta 1

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Cat. No. Species Product Description Structure Purity Feature
IT1-H52W7 Human Human Integrin alpha 6 beta 1 (ITGA6&ITGB1) Heterodimer Protein, His Tag&Tag Free
IT1-H52W7-structure
IT1-H52W7-sds

Integrin alpha 6 beta 1 Molecule Synonym Name

Integrin alpha 6 beta 1,ITGA6&ITGB1

Integrin alpha 6 beta 1 Molecule Background

Integrin alpha 6 beta 1, also called platelet glycoprotein GPIc-IIa, is a receptor for laminin on platelets. The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. ITGA6 has been shown to interact with TSPAN4 and GIPC1.

Integrin alpha 6 beta 1 References

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