TSLP R Protein - ACROBiosystems

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TSLP R


TSR-H525a	Human	Human TSLP R Protein, Fc Tag

Cat. No.

Species

Product Description

Structure

Purity

Feature

TSR-H525a

Human

Human TSLP R Protein, Fc Tag

Part of Bioactivity data

TSR-H525a-SPR

Captured Human TSLP, His Tag (Cat. No. TSP-H52Hb) on CM5 Chip via anti-His antibody, can bind Human TSLP R, Fc Tag (Cat. No. TSR-H525a) with an affinity constant of 1.81 nM as determined in SPR assay (Biacore T200) (Routinely tested).

Protocol

TSR-H525a-SPR

Captured Human TSLP (R127A, R130A), His Tag (Cat. No. TSP-H52Ha) on CM5 Chip via anti-His antibody, can bind Human TSLP R, Fc Tag (Cat. No. TSR-H525a) with an affinity constant of 4.22 nM as determined in SPR assay (Biacore T200) (Routinely tested).

Protocol

Synonym Name

TSLP R,CRLF2,IL-XR,ILXR, p2RY8/CRLF2 fusion,TSLP receptor,TSLPR,CRL2,CRLF2Y,Cytokine receptor-like 2

Background

Receptor for thymic stromal lymphopoietin (TSLP). CRLF2 / TSLPR is a member of the type I cytokine receptor family. Together with the interleukin 7 receptor (IL7R) and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system.

Clinical and Translational Updates