CA125

CA125 Molecule Information

Name：Mucin-16
Target Synonym：Mucin-16?CA125?Ovarian carcinoma antigen CA125?CA-125?MUC16?MUC-16?Ovarian cancer-related tumor marker CA125

Number of Launched Drugs：0
Number of Drugs in Clinical Trials：4
Lastest Research Phase：Phase ?

CA125 Protein Product ListCompare or Buy

Cat. No.	Species	Product Description	Structure	Purity	Feature
CA5-H82F4	Human	Biotinylated Human CA125 / MUC16 Protein, Fc Tag, Avi Tag (Avitag™)

CA125 Molecule Synonym Name

CA125, CA-125, CA125MUC-16, FLJ14303, MUC16, mucin 16, mucin-16

CA125 Molecule Background

The CA125, also known as the MUC16, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. The CA 125 molecule is almost certainly a glycoprotein with a predominance of O-linkages. It is heterogeneous with regard to both size and charge, most likely due to continuous deglycosylation of side chains during its life-span in bodily fluids. It exists as a very large complex (perhaps as much as 4 million daltons) under natural conditions.

CA125 References

CA125 Clinical Drug Information

Name	Research Code	Research Phase	Company	Indications	Clinical Trials
RG-7882	RG-7882; D-4064A; DMUC-4064A	Phase Ⅰ	Genentech	Ovarian cancer, Pancreatic cancer	Details
Oregovomab	B43.13	Phase Ⅱ	Paladin Pharma, National Cancer Institute, Quest PharmaTech, University of Nebraska Medical Center	Ovarian cancer, Pancreatic cancer	Details
Sofituzumab vedotin	RG-7458; DMUC-5754A	Phase Ⅰ	Genentech	Fallopian tube cancer, Peritoneum cancer, Ovarian cancer, Pancreatic cancer	Details
JCAR-020	JCAR-020	Phase Ⅰ	Memorial Sloan-Kettering Cancer Center, Juno Therapeutics	Ovarian cancer	Details