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Your Position: Home > CD37

CD37

Brief Information

Name:Leukocyte antigen CD37
Target Synonym:CD37,Tetraspanin-26,CD37 Molecule,CD37 Antigen,Tspan-26,TSPAN26,Cell Differentiation Antigen 37,Leukocyte Surface Antigen CD37,Leukocyte Antigen CD37,GP52-40
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:6
Lastest Research Phase:Phase 2 Clinical

Licensing

Project Name Modality Therapeutic Area Indications Stage Right Available
CD37+CD22 CAR-T Cell therapy Oncology/Cancer AML PCC Global

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Cat. No. Species Product Description Structure Purity Feature
CD7-H52P4 Human Human CD37 Full Length Protein (VLP)
CD7-H52H3 Human Human CD37 Protein, His Tag
CD7-H52H3-structure
CD7-H52H3-sds
CD7-HF26x Human FITC-Labeled Human CD37 Protein, Fc Tag
CD7-HF26x-structure
CD7-HF26x-sds
CD7-H525a Human Human CD37 Protein, Fc Tag (MALS verified)
CD7-H525a-structure
CD7-H525a-sds
CD7-H526x Human Human CD37 Protein, Fc Tag
CD7-H526x-structure
CD7-H526x-sds
ACRO Quality

Part of Bioactivity data

CD7-H525a-MALS-HPLC
Human CD37, Fc Tag (Cat. No. ) MALS images

The purity of Human CD37, Fc Tag (Cat. No. CD7-H525a) is more than 90% and the molecular weight of this protein is around 95-105 kDa verified by SEC-MALS.

Report
  • Background
    Leukocyte antigen CD37 (CD37) is also known as Tetraspanin-26 (Tspan-26) and TSPAN26,which is a member of the transmembrane 4 superfamily or tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins encoded by CD37 gene mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD37 is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. CD37 may play a role in T-cell-B-cell interactions.
  • Clinical and Translational Updates
      

  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

    CD7-H52P4-ELISA
    CD37 ELISA

    Immobilized Human CD37 Full Length Protein (VLP) (Cat. No. CD7-H52P4) at 5 μg/mL (100 μL/well) can bind Anti-CD37 antibody (Naratuximab), Human IgG1 with a linear range of 0.1-0.8 ng/mL (QC tested).

    Protocol

Synonym Name

CD37,Tspan-26,TSPAN26

Background

Leukocyte antigen CD37 (CD37) is also known as Tetraspanin-26 (Tspan-26) and TSPAN26,which is a member of the transmembrane 4 superfamily or tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins encoded by CD37 gene mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD37 is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. CD37 may play a role in T-cell-B-cell interactions.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
CAR-37 T cell therapy (Massachusetts General Hospital) Phase 1 Clinical Massachusetts General Hospital Hematologic Neoplasms; Leukemia; Lymphoma, B-Cell; Lymphoma, T-Cell; Lymphoma; Lymphoma, Non-Hodgkin Details
AGS-67E AGS-67E Phase 1 Clinical Agensys Inc Leukemia, Hairy Cell; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Leukemia, Lymphocytic, Chronic, B-Cell Details
Lutetium (177lu) lilotomab satetraxetan 177Lu-DOTA-HH1 Phase 2 Clinical Nordic Nanovector Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Follicular; Lymphoma, Non-Hodgkin Details
Ivicentamab GEN-3009 Phase 2 Clinical Genmab A/S, Abbvie Inc Lymphoma, B-Cell; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Follicular; Lymphoma, Mantle-Cell; Leukemia, Lymphocytic, Chronic, B-Cell Details
Naratuximab emtansine IMGN-529; K7153A-SMCC-DM1 Phase 2 Clinical Immunogen Inc Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Leukemia, Lymphocytic, Chronic, B-Cell Details
QLP-31907 QLP-31907; QLP31907; PSB-202 Phase 1 Clinical Qilu Pharmaceutical Co Ltd Lymphoma, B-Cell, Marginal Zone; Lymphoma, B-Cell; Lymphoma, Follicular; Lymphoma, Mantle-Cell; Waldenstrom Macroglobulinemia; Lymphoma, Non-Hodgkin; Leukemia, Lymphocytic, Chronic, B-Cell Details

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