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Your Position: Home > CD37

CD37

Brief Information

Name:Leukocyte antigen CD37
Target Synonym:CD37,Tetraspanin-26,CD37 Molecule,CD37 Antigen,Tspan-26,TSPAN26,Cell Differentiation Antigen 37,Leukocyte Surface Antigen CD37,Leukocyte Antigen CD37,GP52-40
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:6
Lastest Research Phase:Phase 2 Clinical

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Part of Bioactivity data

CD7-H525a-ELISA
Human CD37, Fc Tag (Cat. No. ) MALS images

The purity of Human CD37, Fc Tag (Cat. No. CD7-H525a) is more than 90% and the molecular weight of this protein is around 95-105 kDa verified by SEC-MALS.

  • Background
    Leukocyte antigen CD37 (CD37) is also known as Tetraspanin-26 (Tspan-26) and TSPAN26,which is a member of the transmembrane 4 superfamily or tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins encoded by CD37 gene mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD37 is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. CD37 may play a role in T-cell-B-cell interactions.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

Synonym Name

CD37,Tspan-26,TSPAN26

Background

Leukocyte antigen CD37 (CD37) is also known as Tetraspanin-26 (Tspan-26) and TSPAN26,which is a member of the transmembrane 4 superfamily or tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins encoded by CD37 gene mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD37 is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. CD37 may play a role in T-cell-B-cell interactions.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
CAR-37 T cell therapy (Massachusetts General Hospital) Phase 1 Clinical Massachusetts General Hospital Leukemia; Lymphoma, B-Cell; Hematologic Neoplasms; Lymphoma; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell Details
AGS-67E AGS-67E Phase 1 Clinical Agensys Leukemia, Hairy Cell; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Leukemia, Lymphocytic, Chronic, B-Cell Details
Lutetium (177lu) lilotomab satetraxetan 177Lu-DOTA-HH1 Phase 2 Clinical Nordic Nanovector Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Follicular; Lymphoma, Non-Hodgkin Details
BI-836826 mAb-37.1; mAb-37.2; BI-836826 Phase 2 Clinical C.H. Boehringer Sohn Ag & Co. Kg Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Leukemia, Lymphocytic, Chronic, B-Cell Details
Naratuximab emtansine IMGN-529; K7153A-SMCC-DM1 Phase 2 Clinical Immunogen Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Leukemia, Lymphocytic, Chronic, B-Cell Details
Ivicentamab GEN-3009 Phase 2 Clinical Genmab, Abbvie Inc Lymphoma, B-Cell; Lymphoma, Non-Hodgkin Details

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