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CTGF

CTGF Protein Product ListCompare or Buy

Cat. No. Species Product Description Structure Purity Feature
CTF-M52Hc Mouse Mouse CTGF / CCN2 Protein
CTF-M52Hc-structure
CTF-M52Hc-sds
CTF-H52H5 Human Human CTGF / CCN2 Protein
CTF-H52H5-structure
CTF-H52H5-sds
CTF-H82E6 Human Biotinylated Human CTGF / CCN2 Protein, His Tag, Avi Tag (Avitag™)
CTF-H82E6-structure
CTF-H82E6-sds

CTGF Molecule Synonym Name

CCN2, NOV2, HCS24, IGFBP8, IBP-8, IGFBP-8, IGF-binding protein 8

CTGF Molecule Background

Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CCN1-6) family of modular matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein domain, a vWF-C domain, a TSP-1 domain, and a cysteine knot heparin-binding domain. CTGF promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. Analysis of CCN2 function in vivo has focused primarily on its key role as a mediator of excess ECM synthesis in multiple fibrotic diseases.

CTGF References

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