TPBG Overview
Molecule Name
Trophoblast glycoprotein
Synonyms
TPBG,5T4,M6P1,5T4AG,WAIF1,5T4 oncofetal antigen,Trophoblast glycoprotein,5T4 oncofetal trophoblast glycoprotein
Drug Development Progress
Drugs in Clinical Trials16
Approved Drugs0
Highest Development StagePhase 2 Clinical
Target Synonym
Trophoblast glycoprotein，5T4 oncotrophoblast glycoprotein，5T4，TPBG，5T4 oncofetal antigen，M6P1，5T4 oncofetal trophoblast glycoprotein，Wnt-Activated Inhibitory Factor 1，WAIF1，5T4AG，5T4-AG
Background
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues.This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. TPBG is expressed by all types of trophoblasts as early as 9 weeks of development.
TPBG Product List
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Antibody Project Trading Platform
| Project Name | Project Stage | Molecule Type | Molecule Source | Disease Area | Indication |
|---|---|---|---|---|---|
| 5T4 mAb - 01 | Lead | Monoclonal | Humanized Mouse | Solid Tumor | Ovarian cancer,Lung cancer |
- Project Name
- 5T4 mAb - 01
- Project Stage
- Lead
- Molecule Type
- Monoclonal
- Molecule Source
- Humanized Mouse
- Disease Area
- Solid Tumor
- Indication
- Ovarian cancer,Lung cancer