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Your Position: Home > TPBG

TPBG

TPBG Molecule Information

Name:Trophoblast glycoprotein
Target Synonym:Trophoblast glycoprotein;Wnt-activated inhibitory factor 1;5T4;WAIF1;M6P1;5T4 oncotrophoblast glycoprotein;5T4 oncofetal trophoblast glycoprotein;TPBG;5T4 oncofetal antigen

Number of Launched Drugs:0
Number of Drugs in Clinical Trials:6
Lastest Research Phase:Phase ?

TPBG Protein Product ListCompare or Buy

Product> Filter Results

Cat. No.	Species	Product Description	Structure	Purity	Feature
TPG-H52E5	Human	Unconjugated Human TPBG / 5T4 Protein, His,Avitag™
TPG-H82Eb	Human	Biotinylated Human TPBG / 5T4 Protein, His,Avitag™

TPBG Molecule Synonym Name

TPBG,5T4, M6P1,5T4AG,WAIF1,5T4M6P1,WAIF1,5T4 oncofetal antigen,Trophoblast glycoprotein,5T4 oncofetal trophoblast glycoprotein

TPBG Molecule Background

Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues.This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. TPBG is expressed by all types of trophoblasts as early as 9 weeks of development.

TPBG References

TPBG Clinical Drug Information

Name	Research Code	Research Phase	Company	Indications	Clinical Trials
SYD-1875	SYD-1875	Phase Ⅰ	Synthon	Solid tumours	Details
Prostate cancer vaccine, inactivated viral (University of Oxford)		Phase Not Specified	University of Oxford	Prostate cancer	Details
CME-548 (Oxford biomedica/Pfizer)	CME-548	Preclinical	Oxford BioMedica, Pfizer	Cancer	Details
OXB-301	OXB-301; SAR-109659	Phase Ⅲ	Oxford BioMedica, Cardiff University, University College London, Wales Cancer Trials Unit	Clear cell renal cell cancer (ccRCC)	Details
PET imaging agent (ImaginAb/Oxford BioMedica)		Preclinical	ImaginAb, Oxford BioMedica	Ovarian cancer	Details
PF-06263507	PF-06263507	Phase Ⅰ	Oxford BioMedica, Pfizer	Solid tumours	Details
Naptumomab estafenatox	ABR-217620; TTS-CD3,ABR217620,TTSCD3	Phase Ⅲ	Active Biotech	Advanced renal cell carcinoma (RCC)	Details