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Your Position: Home > TPBG

TPBG

TPBG Molecule Information

Name:Trophoblast glycoprotein
Target Synonym:Trophoblast glycoprotein,5T4 oncotrophoblast glycoprotein,5T4,TPBG,5T4 oncofetal antigen,M6P1,5T4 oncofetal trophoblast glycoprotein,Wnt-Activated Inhibitory Factor 1,WAIF1,5T4AG,5T4-AG

Number of Launched Drugs:0
Number of Drugs in Clinical Trials:4
Lastest Research Phase:Phase 3 Clinical

TPBG Protein Product ListCompare or Buy

Product> Filter Results

Cat. No.	Species	Product Description	Structure	Purity	Feature
TPG-H52E5	Human	Unconjugated Human TPBG / 5T4 Protein, His,Avitag™
TPG-H82Eb	Human	Biotinylated Human TPBG / 5T4 Protein, His,Avitag™

TPBG Molecule Synonym Name

TPBG,5T4, M6P1,5T4AG,WAIF1,5T4M6P1,WAIF1,5T4 oncofetal antigen,Trophoblast glycoprotein,5T4 oncofetal trophoblast glycoprotein

TPBG Molecule Background

Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues.This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. TPBG is expressed by all types of trophoblasts as early as 9 weeks of development.

TPBG References

TPBG Clinical Drug Information

Name	Research Code	Research Phase	Company	Indications	Clinical Trials
Prostate cancer vaccine, inactivated viral (University of Oxford)		Clinical	University Of Oxford	Prostatic Neoplasms	Details
OXB-301	OXB-301; SAR-109659	Phase 3 Clinical	Oxford Biomedica	Carcinoma, Renal Cell; Prostatic Neoplasms	Details
SYD-1875	SYD-1875	Phase 1 Clinical	Synthon Bv	Neoplasms	Details
GEN-1044	GEN-1044	Phase 2 Clinical	Genmab	Esophageal Neoplasms; Neoplasms; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Prostatic Neoplasms; Uterine Neoplasms; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung	Details