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Rituximab

Rituximab Part of Bioactivity data

RIB-Y36-Cell-based assay
FACS assay shows that recombinant Biotinylated FACS

FACS analysis shows that the binding of rituximab to 293F overexpressing CD20 was inhibited by increasing concentration of Anti-Rituximab Antibodies (Cat. No. RIB-Y36). The concentration of rituximab used is 10 ng/ml. The IC50 is 0.025 μg/ml (Routinely tested).

RIB-Y37-Cell-based assay
FACS assay shows that recombinant Biotinylated FACS

FACS analysis shows that the binding of rituximab to 293F overexpressing CD20 was inhibited by increasing concentration of Anti-Rituximab Antibodies (Cat. No. RIB-Y37). The concentration of rituximab used is 10 ng/ml. The IC50 is 0.019 μg/ml (Routinely tested).

RIB-Y36-SPR
Human_FcRn_Heterodimer_Protein_SPR

Anti-Rituximab Antibodies (mouse IgG1, Cat. No. RIB-Y36) captured on CM5 chip via anti-mouse antibodies surface, can bind human rituximab with an affinity constant of 0.01 nM.

RIB-Y35-SPR
Human_FcRn_Heterodimer_Protein_SPR

Anti-Rituximab Antibodies (mouse IgG1, Cat. No. RIB-Y35) captured on CM5 chip via anti-mouse antibodies surface, can bind Human rituximab with an affinity constant of 0.03 nM.

Rituximab Protein Product ListCompare or Buy

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By Conjugate:
Cat. No. Species Product Description Structure Purity Feature
RIB-Y36 Mouse Anti-Rituximab Antibodies (recommended for ADA assay)
RIB-Y36-sds
RIB-Y36-elisa_1
RIB-Y36-elisa_2
RIB-Y37 Mouse Anti-Rituximab Antibodies (recommended for PK/PD)
RIB-Y37-sds
RIB-Y37-elisa_1
RIB-Y35 Mouse Anti-Rituximab Antibodies
RIB-Y35-sds
RIB-Y35-elisa_1
RIB-Y35-elisa_2

Rituximab Molecule Synonym Name

Rituximab Molecule Background

Rituxan is a genetically engineered chimeric murine/human monoclonal antibody directed against the CD20 antigen found on the surface of normal and malignant B lymphocytes. The antibody is an IgG1 kappa immunoglobulin containing murine light- and heavy-chain variable region sequences and human constant region sequences. Rituximab is composed of two heavy chains of 451 amino acids and two light chains of 213 amino acids

Rituximab References

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