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PSCA Molecule Information

Name:Prostate stem cell antigen
Target Synonym:PSCA
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:4
Lastest Research Phase:Phase ?

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Cat. No. Species Product Description Structure Purity Feature
PSA-H52H6 Human Human PSCA Protein, His Tag

PSCA Molecule Synonym Name


PSCA Molecule Background

The Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored protein, plays an important role in tumorigenesis. The prostate stem cell antigen (PSCA) gene, which encodes a prostate-specific antigen (PSA), was identified as a gene involved in cell adhesion and proliferation. PSCA may be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro. May act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits nicotine-induced signaling probably implicating alpha-3:beta-2- or alpha-7-containing nAChRs.

PSCA References

PSCA Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
124-iodine-labeled PSCA targeting minibody (ImaginAb) Phase Ⅰ University of California at Los Angeles, ImaginAb Prostate cancer, Bladder cancer, Pancreatic cancer Details
Anti-PSCA-A11-antibody-I-124 (ImaginAb) Phase Ⅰ University of California, ImaginAb Prostate cancer, Bladder cancer, Pancreatic cancer Details
Anti-PSCA monoclonal antibody (Agensys) AGS-1C4D4; AGS-PSCA; MK-4721 Phase Ⅱ Agensys Prostate cancer, Pancreatic cancer Details
BPX-601 BPX-601 Phase Ⅱ Bellicum Gastric cancer, Prostate cancer, Esophageal adenocarcinoma, Bladder cancer, Pancreatic cancer Details

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