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Project Name Modality Therapeutic Area Indications Stage Right Available
DHODH inhibitor Small molecule Alimentary disease inflammatory bowel disease IND Global
5-HT1F agonist Small molecule Neurological disease Migraine Phase I Global
Capsid Assembly Inhibitors for HBV Small molecule Infectious and parasitic diseases HBV Phase III Global  (except China)
PI3Kδ inhibitor Small molecule Oncology/Cancer Hematologic malignancies Phase I Global
Capsid Assembly Inhibitors for HBV Small molecule Infectious and parasitic diseases HBV Phase I Global  (except China)
RET high selective inhibitor Small molecule Oncology/Cancer NSCLC,Medullary thyroid cancer,Thyroid cancer Phase I Global
A SSRI & Partial 5-HT1A Agonist Small molecule Neurological disease Depression Phase III Global
sGC stimulator Small molecule Cardiovascular PAH,CTEPH,HFrEF,CKD Phase I Global
XO/URAT1 Dual target inhibitors for HUA Small molecule Metabolic disease Hyperuricimia Phase I Global
FXR Agonist Small molecule Metabolic disease NASH Phase II Global
SGLT2 inhibitor Small molecule Metabolic disease Diabetes Phase III Global  (except China)
FXR Agonist Small molecule Metabolic disease Diabetic kidney disease Phase I Global
ACC inhibitor treating NASH Small molecule Metabolic disease NASH IND Global
Oxazolidone (new compounds) antibiotics Small molecule Infectious and parasitic diseases gram-positive bacterial infections IND Global
NF-kB inhibitor (Novel small molecule drug) for cancer cachexia Small molecule Oncology/Cancer Cancer cachexia PCC Global
HIF-PHs inhibitor for CKD and Renal anemia Small molecule Blood and Clotting disease CKD,Renal anemia Phase I Global  (except China)
PI3K/mTOR dual inhibitor Small molecule Oncology/Cancer,Respiratory disease IPF,solid tumor Phase I Global  (except China)
EED inhibitor Small molecule Oncology/Cancer Solid tumor,Hematological malignancy IND Global
Viscous Gel Temozolomide Small molecule Oncology/Cancer,Neurological disease Glioblastoma Phase I Global except CIA
Modified vilazodone Small molecule Neurological disease Major Depressive Disorder BE Global
PI3Kδ inhibitor Small molecule Oncology/Cancer Advanced solid tumors Phase I Global
PARP inhibitor Small molecule Oncology/Cancer Advanced malignant solid tumors Phase I Global
DHODH inhibitor Small molecule Oncology/Cancer Small cell lung cancer IND Global
FXIα inhibitor Small molecule Blood and Clotting disease Arterial thrombosis,Phlebothrombosis,Thrombosis Phase I Global  (except China)
Liver-Targeting THR-β Agonist Small molecule Metabolic disease Nonalcoholic Steatohepatitis (NASH) Phase I Global
PI3Kδ inhibitor Small molecule Oncology/Cancer Solid tumor,Hematological malignancies PCC Global

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Part of Bioactivity data

DB-02-MALS-HPLC
 - ELISA

2% serum diluted by Dilution Buffer : Biotinylated SARS-CoV-2 S protein RBD was put into, the background value is 2.383 and 2.148; 2% serum diluted by DB-02 : Biotinylated SARS-CoV-2 S protein RBD was put into, the background value is 0.262 and 0.263. In the existence of DB-02, the serum background values significantly decreased. Note: Dilution Buffer is Wash Buffer with 0.5% (w/v) bovine serum albumin (BSA), 50 mL.

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