0
There is no goods in the shopping cart !
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Home > Complement C5

Complement C5

Complement C5 Protein Product ListCompare or Buy

Cat. No. Species Product Description Structure Purity Feature
CO5-H52H7 Human Human Complement C5 (w917s) Protein, His Tag
CO5-H52H7-structure
CO5-H52H7-sds
CO5-H52H7-elisa_1
CO5-H52Hx Human Human Complement C5 (R885H) Protein, His Tag
CO5-H52Hx-structure
CO5-H52Hx-sds
CO5-H52Hx-elisa_1
CO5-C52Hx Cynomolgus Cynomolgus Complement C5 Protein, His Tag
CO5-C52Hx-structure
CO5-C52Hx-sds
CO5-C52Hx-elisa_1
CO5-R52H5 Rat Rat Complement C5 Protein, His Tag
CO5-R52H5-structure
CO5-R52H5-sds
CO5-R52H5-elisa_1
CO5-M52H4 Mouse Mouse Complement C5 Protein, His Tag
CO5-M52H4-structure
CO5-C5217 Cynomolgus Cynomolgus Complement C5 Protein, Tag Free
CO5-C5217-structure
CO5-H52Ha Human Human Complement C5 Protein, His Tag
CO5-H52Ha-structure
CO5-H52Ha-sds

Complement C5 Molecule Synonym Name

Complement C5,C5,CPAMD4

Complement C5 Molecule Background

Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. C5 precursor is first processed by the removal of 4 basic residues, forming two chains, beta and alpha, linked by a disulfide bond. C5 convertase activates C5 by cleaving the alpha chain, releasing C5a anaphylatoxin and generating C5b (beta chain + alpha' chain). Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled. The C5a anaphylatoxin interacts with C5AR1 and tick complement inhibitor. C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation.

Complement C5 References

This web search service is supported by Google Inc.

totop