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Your Position: Home > Fc gamma RIV / CD16-2

Fc gamma RIV / CD16-2

Fc gamma RIV / CD16-2 Part of Bioactivity data

FC4-M52H3-SPR
Human_FcRn_Heterodimer_Protein_SPR

Captured Mouse CD16-2, His Tag (Cat. No. FC4-M52H3) on NTA-Series S sensor chip can bind OKT3 with an affinity constant of 154 nM as determined in a SPR assay (Biacore T200) (Routinely tested).

FC4-M82E8-BLI
Human_FcRn_Heterodimer_Protein_Bli

Biotinylated Mouse Fc gamma RIV, His,Avitag (BLI verified) (Cat. No. FC4-M82E8) on SA Biosensor, can bind Rituximab with an affinity constant of 0.394 μM as determined in BLI assay (ForteBio Octet Red96e) (QC tested).

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Cat. No. Species Product Description Structure Purity Feature
FC4-M82E8 Mouse Biotinylated Mouse Fc gamma RIV / CD16-2 Protein, His,Avitag™ (BLI verified)
FC4-M82E8-structure
FC4-M82E8-sds
FC4-M82E8-elisa_1
FC4-M52H3 Mouse Mouse Fc gamma RIV / CD16-2 Protein, His Tag
FC4-M52H3-structure
FC4-M52H3-sds
FC4-M52H3-elisa_2

Fc gamma RIV / CD16-2 Customer Reviews

Fc gamma RIV / CD16-2 Molecule Synonym Name

Fc gamma RIV,CD16-2,Fcgr4

Fc gamma RIV / CD16-2 Molecule Background

FcgR4(Low affinity immunoglobulin gamma Fc region receptor IV) is also known as CD16-2, FcgammaRIV, receptor for the Fc region of immunoglobulin gamma . Also acts as a receptor for the Fc region of immunoglobulin epsilon . Binds with intermediate affinity to both IgG2a and IgG2b . Does not display binding to IgG1 or IgG3. Plays a role in promoting bone resorption by enhancing osteoclast differentiation following binding to IgG2a. Binds with low affinity to both the a and b allotypes of IgE. Has also been shown to bind to IgE allotype a only but not to allotype b. Binding to IgE promotes macrophage-mediated phagocytosis, antigen presentation to T cells, production of proinflammatory cytokines and the late phase of cutaneous allergic reactions

Fc gamma RIV / CD16-2 References

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