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Your Position: Home > IL-15 R alpha

IL-15 R alpha

IL-15 R alpha Protein Product ListCompare or Buy

Product> Filter Results

Cat. No.	Species	Product Description	Structure	Purity	Feature
ILA-H82F4	Human	Biotinylated Human IL-15 R alpha / CD215 Protein, Fc,Avitag™
ILA-H5253	Human	Human IL-15 R alpha / CD215 Protein, Fc Tag

IL-15 R alpha Part of Bioactivity data

ILA-H5253-Cell-based assay

Human FcRn Heterodimer Protein Cell_Base

Human IL-15 R alpha, Fc Tag (Cat. No. ILA-H5253) inhibits IL-15-dependent proliferation of CTLL-2 cells. The ED50 for this effect is 2.77-4.20 ng/mL (Routinely tested).

Protocol

ILA-H5253-ELISA

Immobilized Human IL-15 R alpha, Fc Tag (Cat. No. ILA-H5253) at 2 μg/mL (100 μL/well) can bind Biotinylated Human IL-15, Fc,Avitag (Cat. No. IL5-H82F3) with a linear range of 2-78 ng/mL (QC tested).

Protocol

Immobilized Human IL-15, Tag Free (Cat. No. IL5-H4117) at 2 μg/mL (100 μL/well) can bind Biotinylated Human IL-15 R alpha, Fc,Avitag (Cat. No. ILA-H82F4) with a linear range of 2-39 ng/mL (QC tested).

Protocol

IL-15 R alpha Molecule Synonym Name

IL-15 R alpha,CD215,IL15RA,IL-15RA,IL-15R-alpha

IL-15 R alpha Molecule Background

IL15R is a heterotrimer of IL15RA, IL2RB and IL2RG. IL-15RA, also known as CD215, IL-15 R alpha, is a widely expressed 60 kDa transmembrane glycoprotein. High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Expression of different isoforms may alter or interfere with signal transduction. An interleukin (IL)-15 superagonist/IL-15 receptor ? fusion complex (IL-15SA/IL-15RA; ALT-803) activates the IL-15 receptor on CD8 T cells and NK cells, and has shown significant anti-tumor. Signal transduction involves SYK. Higher levels of soluble sIL-15RA form in comparison with membrane-bound forms is present in all brain structures.