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Your Position: Home > Glypican 1

Glypican 1

Brief Information

Name:Glypican-1
Target Synonym:Epididymis Secretory Sperm Binding Protein,GPC1,Glypican 1,Glypican Proteoglycan 1,Glypican-1,Glypican,GPC-1
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 1 Clinical

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Part of Bioactivity data

GP1-H52H9-ELISA
Human Glypican 1, His TagHuman Glypican 1, His Tag (Cat. No. GP1-H52H9) ELISA bioactivity

Immobilized Human FGF basic, Tag Free (Cat. No. BFF-H4117) at 1 μg/mL (100 μL/well) can bind Human Glypican 1, His Tag (Cat. No. GP1-H52H9) with a linear range of 2-39 ng/mL (QC tested).

GP1-H52H8-MALS-HPLC
Human Glypican 1 (S486A, S488A, S490A), His Tag (Cat. No. ) MALS images

The purity of Human Glypican 1 (S486A, S488A, S490A), His Tag (Cat. No. GP1-H52H8) is more than 90% and the molecular weight of this protein is around 53-68 kDa verified by SEC-MALS.

  • Background
    Glypican 1 has been shown to interact with SLIT2. This protein is involved in the misfolding of normal prion proteins in the cell membrane to the infectious prion form. Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

Synonym Name

Glypican 1,GPC1

Background

Glypican 1 has been shown to interact with SLIT2. This protein is involved in the misfolding of normal prion proteins in the cell membrane to the infectious prion form. Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
MILGa MIL-38/Gallium67 Phase 1 Clinical Glytherix Pancreatic Neoplasms; Urinary Bladder Neoplasms; Prostatic Neoplasms Details

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