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Glypican 1

Brief Information

Target Synonym:Epididymis Secretory Sperm Binding Protein,GPC1,Glypican 1,Glypican Proteoglycan 1,Glypican-1,Glypican,GPC-1
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 1 Clinical

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ACRO Quality

Part of Bioactivity data

 Glypican 1 ELISA

Immobilized Human FGF basic, premium grade (Cat. No. BFF-H4117) at 1 μg/mL (100 μL/well) can bind Mouse Glypican 1, His Tag (Cat. No. GP1-M52H7) with a linear range of 5-78 ng/mL (QC tested).

Glypican 1 MALS images

The purity of Biotinylated Human Glypican 1 Protein, His,Avitag (Cat. No. GP1-H82E3) is more than 90% and the molecular weight of this protein is around 55-75 kDa verified by SEC-MALS.

Synonym Name

Glypican 1,GPC1


Glypican 1 has been shown to interact with SLIT2. This protein is involved in the misfolding of normal prion proteins in the cell membrane to the infectious prion form. Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Miltuximab MIL-38/Gallium67 Phase 1 Clinical Glytherix Pancreatic Neoplasms; Urinary Bladder Neoplasms; Prostatic Neoplasms Details

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