|EP130-C03||Biotinylated Human PD-L1||20μg|
|EP130-C04||Anti-PD-1 Neutralizing Antibody||20μg|
The inhibitor screening ELISA kit is designed to facilitate the identification and characterization of new PD-1 pathway inhibitors.
It is for research use only.
Your experiment will include 4 simple steps:
a) Coat the plate with human PD-1.
b) Add your molecule of interest to the tests.
c) Add human PD-L1-Biotin to bind the coated human PD-1.
d) Add Streptavidin-HRP followed by TMB or other colorimetric HRP substrate.
Finally, the half maximal inhibitory concentration (IC50) of your compound to PD-1: PD-L1 binding will be determined by comparing OD readings among different experimental groups.
INHIBITION OF PD-1: PD-L1 [BIOTINYLATED] BINDING BY ANTI-BAFFR NEUTRALIZING ANTIBODY
Serial dilutions of Anti-PD-1 Neutralizing antibody (Catalog # EP130-C04) (1:1 serial dilution, from 5μg/mL to 0.02μg/mL) was added into PD-1: Biotinylated PD-L1 binding reactions. The assay was performed according to the protocol described below. Background was subtracted from data points prior to log transformation and curve fitting (QC tested).
Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.
Price(USD) : $600.00
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