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Your Position: Home > Protein > CD48 > BC1-H5226

Human CD48 / SLAMF2 Protein, His Tag (MALS verified)

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  • Synonym
    CD48,BCM1,SLAMF2,BLAST,BLAST1,MEM-102,TCT.1,BCM-1,SLAMF-2,BLAST-1
  • Source
    Human CD48, His Tag(BC1-H5226) is expressed from human 293 cells (HEK293). It contains AA Gln 27 - Ser 220 (Accession # AAH16182).
    Predicted N-terminus: Gln 27
  • Molecular Characterization
    CD48 Structure

    This protein carries a polyhistidine tag at the C-terminus

    The protein has a calculated MW of 23.2 kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
CD48 SDS-PAGE

Human CD48, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

SEC-MALS
CD48 MALS images

The purity of Human CD48, His Tag (Cat. No. BC1-H5226) is more than 90% and the molecular weight of this protein is around 32-42 kDa verified by SEC-MALS.

Bioactivity-ELISA
 CD48 ELISA

Immobilized Human CD48, His Tag (Cat. No. BC1-H5226) at 10 μg/mL (100 μL/well) can bind Human 2B4, Fc Tag (Cat. No. 2B4-H5255) with a linear range of 0.039-0.625 μg/mL (QC tested).

  • Background
    CD48 antigen is also known as Signaling lymphocytic activation molecule 2, SLAM family member 2 (SLAMF2), Leukocyte antigen MEM-102, BCM1 surface antigen, B-lymphocyte activation marker BLAST-1. CD48 is a 65 kDa GPI-linked protein which belongs to the CD2 subfamily of immunoglobulin superfamily molecules. CD48 antigen contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domain. CD48 interacts with CD244 in an heterophilic manner. CD48 is ligand for CD2. CD48 might facilitate interaction between activated lymphocytes. CD48 is probably involved in regulating T-cell activation.
  • Clinical and Translational Updates

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Price(USD) : $250.00

Price(USD) : $1650.00

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Drug Development Status

  • Number of Launched Drugs:0 Details
  • Number of Drugs in Clinical Trials:0 Details
  • Latest Research Phase:Discontinued

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