Acrobiosystems for English
icon_bulk_orderBulk inquiry/Quick order
There is no goods in the shopping cart !
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Home > Protein > PADI4 > PA4-C5143

Cynomolgus PADI4 Protein, His Tag (active enzyme)

Order Now

  • Synonym
    Protein-arginine deiminase type-4,HL-60 PAD,Peptidylarginine deiminase IV,Protein-arginine deiminase type IV,PADI4,EC:
  • Source
    Cynomolgus PADI4 Protein, His Tag(PA4-C5143) is expressed from E. coli cells. It contains AA Met 1 - Pro 663 (Accession # A0A2K5USI5-1).
  • Molecular Characterization
    PADI4 Structure

    This protein carries a polyhistidine tag at the N-terminus.

    The protein has a calculated MW of 76.1 kDa. The protein migrates as 70-80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Supplied as 0.2 μm filtered solution in 500 mM NaCl, 1 mM EDTA, 2 mM TCEP, pH8.0 with glycerol as protectant.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.

Cynomolgus PADI4 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).


Measured by its ability to catalyze the deimination of benzoyl--arginine ethyl ester. The specific activity is >1000 pmol/min/μg (QC tested).

  • Background
    Protein arginine deiminase, type 4 (PADI4) is a calcium dependent enzyme Catalyzes the citrullination/deimination of arginine residues of proteins such as histones, thereby playing a key role in histone code and regulation of stem cell maintenance. PADI4 can interact with tumor suppressor p53 and regulate the transcriptional activity of p53. Dysregulation of PADI4 is implicated in a variety of diseases, including rheumatoid arthritis, tumor development, and multiple sclerosis.
  • Clinical and Translational Updates

Comments (0)

ETA of in-stock products: 2 business days

Price(USD) : $600.00

Price(USD) : $4200.00

Promotion & Exhibitions

Datasheet & Documentation

Request for DMF
DMF (Drug Master File)

Related Products

New Product Launch

Questions & Comments

This web search service is supported by Google Inc.

Call us
Call us
North America:
+1 800-810-0816 (Toll Free)
Asia & Pacific:
+86 400-682-2521
+1 888-377-6111
1 Innovation Way, Newark, DE 19711, USA

Leave a message