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Your Position: Home > Antibody > CD3 > CDE-PCFP1

PE-Labeled Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a (Clone: OKT3)Star Staining

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  • Source
    PE-Labeled Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a (OKT3) is produced via conjugation of PE to Anti-Human CD3 Antibody, Mouse IgG2a (OKT3) under optimal conditions with a new generation site-specific technology under Star Staining labeling platform.
  • Application
    Flow Cytometry (Detection the expression of CD3 on Human cells).
  • Clone
    OKT3
  • Host Species
    Mouse
  • Isotype
    Mouse IgG2a/kappa
  • Specificity
    This product is a specific antibody specifically reacts with CD3 epsilon protein.
  • Reactivity

    Human

  • Immunogen

    Purified Human CD3ε Protein.

  • Conjugate

    PE

    Excitation Wavelength: 488 nm / 561 nm

    Emission Wavelength: 575 nm

  • Isotype Control

    The Isotype control is sold separately and you can search for Cat. No. DNP-PM487 for product information.

  • Recommended Dilution
    1:50
  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, 0.03% Proclin 300, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 12 months after reconstitution;
    3. 2-8°C for 12 months after reconstitution.
Bioactivity-FACS
 CD3 FACS

Flow cytometric analysis of Jurkat cells staining with PE-Labeled Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a (Clone: OKT3) (Cat. No. CDE-PCFP1) at 1:50 dilution (2μL of the antibody stock solution corresponds to labeling of 1e6 cells in a final volume of 100 µL) , compared with isotype control antibody. PE signal was used to evaluate the binding activity (QC tested).

  • Background
    CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2.
  • Clinical and Translational Updates

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ETA of in-stock products: 2 business days

Price(USD) : $90.00

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Drug Development Status

  • Number of Launched Drugs:7 Details
  • Number of Drugs in Clinical Trials:157 Details
  • Latest Research Phase:Approved

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