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> Variant-specific antibody 
From Alpha to Omicron, the emergence of highly contagious variants continually triggered worldwide epidemics and should be responsible for the increasing cases of breakthrough infection. The efficacy of vaccines and therapeutics was continuously faced with challenges. There have been more than 10 billion doses of vaccines administered globally for protecting people from COVID-19. However, in the three months since the Omicron variant (B.1.1.529) emerged, its toll across the globe has been still devastating; two monoclonal antibody therapies have been removed from the list of COVID-19 treatments.
>>> Click here to find out more information about emerging variants of SARS-CoV-2
To match the needs of next-generation vaccine and therapeutic antibody development, ACROBiosystems has successfully developed a series of variants specific antibodies for VOCs, including Omicron-, Delta- and Beta & Gamma-specific antibody.
| Species | Cat. No. | Product Description | Isotype | Epitope | Preorder/Order |
|---|---|---|---|---|---|
| Omicron | SPD-M305 | Anti-SARS-CoV-2 Spike RBD Antibody, Mouse IgG1 (Omicron Specific) | Mouse IgG1 | Spike RBD | |
| Delta | SPD-M110 | Anti-SARS-CoV-2 Spike RBD Antibody, Mouse IgG1 (Delta Specific) | Mouse IgG1 | Spike RBD | |
| SPD-M370 | Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (Delta Specific) | Mouse IgG1 | Spike RBD | ||
| Beta & Gamma | SPD-M416 | Anti-SARS-CoV-2 Spike RBD Antibody, Mouse IgG1 (AM416) (Beta & Gamma Specific) | Mouse IgG1 | Spike RBD | |
| SPD-M334 | Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (AM416) (Beta & Gamma Specific) (MALS verified) | Human IgG1 | Spike RBD |
Anti-SARS-CoV-2 Spike RBD Antibody, Mouse IgG1 (Delta Specific) (Cat. No. SPD-M110) on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. The purity is more than 95% and the molecular weight of this protein is around 135-155 kDa verified by SEC-MALS.
Immobilized SARS-CoV-2 Spike RBD (Omicron, Cat. No. SPD-C522e) can bind Anti-SARS-CoV-2 Spike RBD Antibody, Mouse IgG1 (Cat. No. SPD-M305) with a linear range of 0.4-12.5 ng/mL. The antibody does not bind Spike RBD of WT (Cat. No. SPD-C52H1), Alpha (Cat. No. SPD-C52Hn), Beta (Cat. No. SPD-C52Hp), Delta (Cat. No. SPD-C52Hh) and Gamma (Cat. No. SPD-C52Hr) (Routinely tested).
Immobilized SARS-CoV-2 Spike RBD (Delta, Cat. No. SPD-C52Hh) can bind Anti-SARS-CoV-2 Spike RBD Antibody, Mouse IgG1 (Cat. No.SPD-M110) with a linear range of 0.1-3 ng/mL. The antibody does not bind Spike RBD of WT (Cat. No. SPD-C52H1), Alpha (Cat. No. SPD-C52Hn), Beta (Cat. No. SPD-C52Hp), Gamma (Cat. No. SPD-C52Hr) and Omicron (Cat. No. SPD-C522e) (QC tested).
Immobilized SARS-CoV-2 spike protein (Beta, Cat. No. SPN-C52Hk and Gamma, Cat. No. SPN-C52Hg) can bind Anti-SARS-CoV-2 Spike Antibody-H6, Mouse IgG1 (AM416) with a linear range of 6-8 ng/mL. The antibody does not bind spike protein of WT (Cat. No. SPN-C52H7), Alpha (Cat. No. SPN-C52H6) and Delta (Cat. No. SPN-C52He) (QC tested).
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