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Your Position: Home > Klotho beta

Klotho beta

Brief Information

Name:Klotho beta
Target Synonym:Klotho Beta,Klotho Beta-Like Protein,B-Klotho,Klotho Beta Like,Beta-Klotho,EC 3.2.1,BKL,BetaKlotho,KLB
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:3
Lastest Research Phase:Phase 2 Clinical

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Part of Bioactivity data

KLB-R52H8-BLI
 Klotho beta BLI

Loaded Human FGF R4, Fc Tag (Cat. No. FG4-H5253) on Protein A Biosensor, can bind Rhesus macaque Klotho beta, His Tag (Cat. No. KLB-R52H8) with an affinity constant of 0.9 μM as determined in BLI assay (ForteBio Octet Red96e) (QC tested).

KLB-R52H8-BLI
 Klotho beta BLI

Loaded Human FGF19, Fc Tag (Cat. No. FG9-H5253) on Protein A Biosensor, can bind Rhesus macaque Klotho beta, His Tag (Cat. No. KLB-R52H8) with an affinity constant of 78.5 nM as determined in BLI assay (ForteBio Octet Red96e) (QC tested).

Synonym Name

betaKlotho,beta-klotho,BKL,KLB,klotho beta like,klotho beta-like protein

Background

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
B-1344 B-1344 Phase 1 Clinical Tasly Biomedical Co Ltd Non-alcoholic Fatty Liver Disease; Diabetes Mellitus, Type 2 Details
Fazpilodemab RG-7992; BFKB-8488A; RO-7040551 Phase 2 Clinical Genentech Inc Non-alcoholic Fatty Liver Disease; Diabetes Mellitus, Type 2; Insulin Resistance Details
NGM-313 NGM-313; MK-3655 Phase 2 Clinical Ngm Biopharmaceuticals Inc Non-alcoholic Fatty Liver Disease; Hepatitis; Obesity Details

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