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HGF R

HGF R Molecule Information

Name:Hepatocyte growth factor receptor
Target Synonym:EC 2.7.10,EC:2.7.10.1,HGF receptor,HGF/SF receptor,Hepatocyte growth factor receptor,Tyrosine-protein kinase Met,MET,SF receptor,Scatter factor receptor,MET Proto-Oncogene, Receptor Tyrosine Kinase,Proto-Oncogene C-Met,Met Proto-Oncogene,EC 2.7.10.1,DFNB9
Number of Launched Drugs:4
Number of Drugs in Clinical Trials:46
Lastest Research Phase:Approved

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HGF R Part of Bioactivity data

MET-H5256-ELISA
Human HGF R, Fc TagHuman HGF R, Fc Tag (Cat. No. MET-H5256) ELISA bioactivity

Immobilized Human HGF, His Tag (Cat. No. HGF-H52H3) at 2 μg/mL (100 μL/well) can bind Human HGF R, Fc Tag (Cat. No. MET-H5256) with a linear range of 0.6-20 ng/mL (QC tested).

MET-H82E1-MALS-HPLC
Biotinylated Human HGF R, Avitag,His Tag (Cat. No. ) MALS images

The purity of Biotinylated Human HGF R, Avitag,His Tag (Cat. No. MET-H82E1) was more than 90% and the molecular weight of this protein is around 125-145 kDa verified by SEC-MALS.

Bioactivity-ELISA
Biotinylated Human HGF R, Avitag,His TagBiotinylated Human HGF R, Avitag,His Tag (Cat. No. MET-H82E1) ELISA bioactivity

Immobilized Human HGF, His Tag (Cat. No. HGF-H52H3) at 2 μg/mL (100 μL/well) can bind Biotinylated Human HGF R, Avitag,His Tag (Cat. No. MET-H82E1) with a linear range of 0.039-0.313 μg/mL (QC tested).

HGF R Molecule Synonym Name

MET,AUTS9,HGFR,RCCP2,c-Met

HGF R Molecule Background

The SARS-CoV-2 Spike S2-coupled Magnetic Beads is produced by coupling biotinylated SARS-CoV-2 spike S2 protein to streptavidin-conjugated magnetic beads. Because Streptavidin (SA) has an extraordinarily high affinity for biotin with a dissociation constant (Kd) on the order of 10-14 mol/L, the biotinylated protein can bind to the SA beads irreversibly. The pre-coupled beads are ready to use for capturing anti-SARS-CoV-2 antibody or ACE2 protein from your sample with high specificity.

HGF R References

HGF R Related Molecule

HGF

HGF R Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Crizotinib PF-1066; PF-2341066; PF-02341066; PF-002341066 Approved Pfizer Pharmaceuticals Ltd (China) 赛可瑞, Xalkori United States Lymphoma, Large-Cell, Anaplastic s:11:"Pf Prism Cv"; 2011-08-26 Kidney Diseases; Lung Neoplasms; Lymphoma, Large-Cell, Anaplastic; Carcinoma, Non-Small-Cell Lung Details
Cabozantinib S-malate XL-184; BMS-907351 Approved Exelixis Inc Cometriq, Cabometyx Japan Carcinoma, Renal Cell s:6:"Takeda"; 2012-11-29 Solid tumours; Stomach Neoplasms; Carcinoma, Renal Cell; Pain; Esophageal Neoplasms; Kidney Diseases; Glioblastoma; Prostatic Neoplasms; Colorectal Neoplasms; Hepatic Insufficiency; Astrocytoma; Thyroid Neoplasms; Lymphoma; Carcinoma, Neuroendocrine; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung Details
Capmatinib Hydrochloride NVP-INC280-NX; INCB-28060; C2A374O70X; INC-280; INCB-028060 Approved Incyte Corp, Novartis Pharma Ag Tabrecta Japan Carcinoma, Non-Small-Cell Lung s:18:"Novartis Pharma Ag"; 2020-05-06 Solid tumours; Liver Neoplasms; Carcinoma; Adenocarcinoma of Lung; Triple Negative Breast Neoplasms; Hepatic Insufficiency; Carcinoma, Squamous Cell; Carcinoma, Non-Small-Cell Lung; Melanoma; Carcinoma, Hepatocellular; Neoplasm Metastasis Details
Tepotinib hydrochloride hydrate EMD-1214063; MSC-2156119; MSC-2156119J Approved Merck Serono テプミトコ, TEPMETKO, Tepmetko United States Carcinoma, Non-Small-Cell Lung s:14:"Emd Serono Inc"; 2020-03-25 Solid tumours; Hepatic Insufficiency; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular Details

HGF R Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
SAIT-301 SAIT-301 Phase 1 Clinical Samung Medical Centre Neoplasms Details
Emibetuzumab LA-480; LY-2875358 Phase 2 Clinical Eli Lilly And Company Liver Neoplasms; Carcinoma, Renal Cell; Stomach Neoplasms; Lymphoma; Adenocarcinoma; Carcinoma, Non-Small-Cell Lung Details
NP-01 (Shijiazhuang No.4 Pharmaceutical/Nanjing Nadingfei Medical Technology) NP-01 Phase 1 Clinical Shijiazhuang No.4 Pharmaceutical Co Ltd, Nanjing Nadingfei Pharmaceutical Technology Co Ltd Liver Neoplasms; Stomach Neoplasms; Lung Neoplasms Details
Boxitinib Hydrochloride Phase 1 Clinical Hec Pharm Co Ltd Stomach Neoplasms; Carcinoma, Renal Cell; Breast Neoplasms; Glioma; Lung Neoplasms Details
Alirinetide GM-6; GM-600; GM-602; GM-603; GM-604; GM-605; GM-606; GM-607; GM-608; GM-609 Phase 2 Clinical Genervon Biopharmaceuticals Llc Stroke; Parkinson Disease; Amyotrophic Lateral Sclerosis Details
CM-118 CM-118 Phase 1 Clinical Xcovery Carcinoma, Non-Small-Cell Lung Details
QBH-196 QBH-196 Phase 1 Clinical Shenyang Pharmaceutical University Stomach Neoplasms Details
ABN-401 ABN-401; KDDF-201603-08 Phase 2 Clinical Abion Inc Neoplasms Details
Sym-015 Sym-015 Phase 2 Clinical Symphogen Lung Neoplasms; Carcinoma, Non-Small-Cell Lung Details
CBT-101 CBT-101 Phase 1 Clinical Crown Bioscience Neoplasms Details
Altiratinib DP-5164; DCC-2701; DCC-22701; T-678746713 Phase 1 Clinical Deciphera Neoplasms Details
TPX-0022 TPX-0022 Phase 1 Clinical Turning Point Therapeutics Neoplasms Details
EMB-01 EMB-01 Phase 2 Clinical Shanghai Epimab Biotherapeutics, Inc Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis Details
XL-092 XL-092 Phase 1 Clinical Exelixis Carcinoma, Renal Cell; Breast Neoplasms; Prostatic Neoplasms Details
Glesatinib MG-90265; MGCD-265; MG-90265X; 7Q29OXD98N; MG-90265H9; MG-90265gly Phase 2 Clinical Mirati Therapeutics Carcinoma, Non-Small-Cell Lung Details
JNJ-38877618 OMO-1; JNJ-38877618 Phase 2 Clinical Johnson & Johnson Neoplasms Details
Anti-cMet SIMPLE Antibody ARGX-111 Phase 1 Clinical Argen-X Neoplasms Details
Refanalin BB-3; SNV-003; ANG-3777 Phase 3 Clinical Angion Biomedica Myocardial Infarction; Pneumonia; Coronavirus Disease 2019 (COVID-19); Delayed Graft Function; Acute Kidney Injury Details
LMV-12(HE003) LMV-12(HE003) Phase 1 Clinical Nanchang Hongyi Technology Co Ltd Neoplasms Details
c-Met/PD-L1 CAR-T cell (The Second Hospital of Nanjing Medical University) Phase 1 Clinical The Second Hospital Of Nanjing Medical University Carcinoma, Hepatocellular Details
RC-108 RC-108; RC108 Phase 1 Clinical Rc Biotechnologies Ltd Solid tumours Details
S-49076 S-49076 Phase 2 Clinical Servier Glioblastoma; Carcinoma, Non-Small-Cell Lung Details
SAR-125844 SAR-125844 Phase 2 Clinical Sanofi Neoplasms; Carcinoma, Non-Small-Cell Lung Details
SPH3348 SPH-3348 Phase 1 Clinical Shanghai Pharmaceuticals Holding Co Ltd Solid tumours Details
ASLAN-002 ASLAN-002; BMS-777607; BMS-797669 Phase 2 Clinical Bristol-Myers Squibb Company Stomach Neoplasms; Neoplasms; Breast Neoplasms Details
SHR-A1403 SHR-A1403 Phase 1 Clinical Jiangsu Hengrui Medicine Co Ltd Solid tumours Details
RXDX-106 RXDX-106 Phase 1 Clinical Teva, Daiichi Sankyo Co Ltd Solid tumours; Neoplasms Details
Glumetinib SCC244; HH-SCC244 Phase 2 Clinical Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences, Shanghai Greenvalley Pharmaceutical Co Ltd Solid tumours; Carcinoma, Non-Small-Cell Lung Details
AMG-337 AMG-337 Phase 2 Clinical Amgen Inc Solid tumours; Stomach Neoplasms; Sarcoma, Clear Cell; Esophageal adenocarcinoma Details
HS-10241 HS-10241 Phase 1 Clinical Jiangsu Hansoh Pharmaceutical Group Co Ltd Liver Neoplasms; Solid tumours; Carcinoma; Stomach Neoplasms; Lung Neoplasms Details
TAS-115 TAS-115 Phase 1 Clinical Taiho Pharmaceutical Co Ltd, Otsuka Pharmaceutical Co Ltd Neoplasms Details
AL-2846 AL-2846 Phase 2 Clinical Advenchen Laboratories Nanjing Ltd, Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd Bone metastases; Liver Neoplasms; Stomach Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms; Medullary thyroid cancer (MTC); Colorectal Neoplasms; Glioma; Carcinoma, Non-Small-Cell Lung Details
Metatinib Trometamol BMS-817378; SIM-817378 Phase 1 Clinical Bristol-Myers Squibb Company Solid tumours; Liver Neoplasms; Stomach Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
GST-HG161 GST-HG161 Phase 1 Clinical Wuxi Apptec Co Ltd, Fujian Cosunter Pharmaceutical Co Ltd Solid tumours; Carcinoma, Hepatocellular Details
Recombinant plasmid-hepatocyte growth factor Pudk-HGF Phase 3 Clinical Wuhan Optical Valley Humanwell Biological Pharmaceutical Co Ltd, Academy Of Military Medical Sciences Ischemia; Peripheral Arterial Disease Details
Kanitinib CX-1003 Phase 1 Clinical Beijing Konruns Pharmaceutical Co Ltd, Guangzhou Esa Biotech Solid tumours; Esophageal Neoplasms; Prostatic Neoplasms Details
Merestinib 5OGS5K699E; LY-2801653 Phase 2 Clinical Eli Lilly And Company Biliary Tract Neoplasms; Solid tumours; Skin Melanoma; Pancreatic Neoplasms; Microsatellite instability-high cancer; Cholangiocarcinoma; Breast Neoplasms; Lymphoma, Mantle-Cell; Colorectal Neoplasms; Gallbladder Neoplasms; Lymphoma, Non-Hodgkin; Neoplasm Metastasis Details
Sitravatinib MG-516; MG-91516; MGCD-516 Phase 3 Clinical Mirati Therapeutics Solid tumours; Carcinoma; Carcinoma, Renal Cell; Neoplasms; Carcinoma, Transitional Cell; Hepatic Insufficiency; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Gastrointestinal Neoplasms Details
Amivantamab JNJ-61186372; JNJ-372 Phase 3 Clinical Janssen Global Services Llc, Genmab Carcinoma, Non-Small-Cell Lung Details
MCLA-129 MCLA-129 Phase 1 Clinical Merus Solid tumours Details
BPI-9016 BPI-9016; BPI-9016M Phase 1 Clinical Betta Pharmaceuticals Co Ltd Solid tumours; Carcinoma, Non-Small-Cell Lung Details
Telisotuzumab vedotin ABT-399; ABBV-399 Phase 2 Clinical Abbvie Inc Solid tumours; Carcinoma, Non-Small-Cell Lung Details
Bozitinib APL-101; CBT-101; CBI-3103; PLB-1001 Phase 2 Clinical Beijing Purunao Biotechnology Co Ltd, Cbt, Heng Kang, Crown Bioscience Kidney Neoplasms; Solid tumours; Stomach Neoplasms; Carcinoma, Renal Cell; Esophageal Neoplasms; Glioblastoma; Ganglioglioma; Brain Neoplasms; Lung Neoplasms; Glioma; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma; Carcinoma, Hepatocellular Details
Ningetinib Tosylate CT-053; CT-053-PTSA Phase 2 Clinical Hec Pharm Co Ltd Intestinal Neoplasms; Solid tumours; Stomach Neoplasms; Carcinoma, Renal Cell; Lung Neoplasms; Leukemia, Myeloid, Acute; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular Details

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