0
There is no goods in the shopping cart !
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Home > GITR

GITR

GITR Molecule Information

Name:Glucocorticoid-induced tumor necrosis factor receptor-related protein
Target Synonym:Glucocorticoid-induced tumor necrosis factor receptor-related protein;CD357;AITR;GITR;Activation-inducible TNFR family receptor;TNFRSF18;UNQ319/PRO364;Glucocorticoid-induced TNFR-related protein
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:12
Lastest Research Phase:Phase ?

GITR Protein Product ListCompare or Buy

GITR Molecule Synonym Name

AITR,GITR,TNFRSF18,CD357

GITR Molecule Background

Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.

GITR References

GITR Related Molecule

GITR Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
ASP-1951 ASP-1951; PTZ-522 Phase Ⅰ Potenza Therapeutics, Astellas Solid tumours Details
Anti-GITR antibody (BMS) Phase Ⅰ Bristol-Myers Squibb Solid tumours Details
MK-1248 MK-1248 Phase Ⅰ Merck Sharp & Dohme Solid tumours Details
Efgivanermin alfa MEDI-1873 Phase Ⅰ MedImmune Solid tumours Details
AMG-228 AMG-228 Phase Ⅰ Amgen Solid tumours Details
OMP-336B11 OMP-336B11 Phase Ⅰ OncoMed Pharmaceuticals Solid tumours Details
TRX-518 TRX-518 Phase Ⅱ Tolerx, Leap Therapeutics Prostate cancer, Solid tumours, Ovarian cancer, Melanoma Details
ATOR-1144 ATOR-1144 Preclinical Alligator Bioscience hematological malignancies, Solid tumours Details
INCAGN-1876 INCAGN-1876 Phase Ⅱ Agenus, Ludwig Institute for Cancer Research, Incyte Solid tumours Details
GWN-323 GWN-323 Phase Ⅰ Novartis Solid tumours, Lymphoma Details
BMS-986156 BMS-986156,BMS 986156 Phase Ⅱ Bristol-Myers Squibb Solid tumours Details
MK-4166 MK-4166 Phase Ⅰ Merck Sharp & Dohme Solid tumours, Glioblastoma Details

This web search service is supported by Google Inc.

totop