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| Project Name | Project Stage | Molecule Type | Host Species | Therapeutic Area | Indications |
| CD7 VHH - 01 | Lead | Hematological Malignancy | Non-hodgkin lymphoma |
1e5 of Mouse Anti-CD7 antibody coupled beads (5.5 μm) were stained with different concentration of Alexa Fluor 647-Labeled Human CD7 Protein, His Tag (Cat. No. CD7-HA2H4) and negative control protein respectively, AF647 signal was used to evaluate the binding activity (QC tested).
1e5 of Mouse Anti-CD7 antibody coupled beads (5.5 μm) were stained with different concentration of Alexa Fluor 647-Labeled Human CD7 Protein, His Tag (Cat. No. CD7-HA2H4) and negative control protein respectively, AF647 signal was used to evaluate the binding activity (QC tested).
Cynomolgus CD7 Protein, His Tag (Cat. No. CD7-C52H7) immobilized on CM5 Chip can bind Human SECTM1, His Tag (Cat. No. SE1-H5227) with an affinity constant of 24.7 nM as determined in a SPR assay (Biacore 8K) (QC tested).
| Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
|---|---|---|---|---|---|
| Anti-CD7 and anti-CD19 chimeric antigen receptor T cell therapy | GC-197 | Phase 2 Clinical | Gracell Biotechnologies (Shanghai) Co Ltd | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma | Details |
| BEAM-201 | BEAM-201 | Phase 2 Clinical | Beam Therapeutics Inc | Leukemia, Lymphoid; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, T-Cell | Details |
| CD7-specific CAR-T Cell therapy(Taihe Chunyu Biotechnology) | Phase 2 Clinical | Hebei Tahoe Chunyu Biotechnology Co Ltd | Hematologic Neoplasms | Details | |
| CD7 CAR-T cell therapy(The General Hospital Of Western Theater Command) | Phase 2 Clinical | The General Hospital Of Western Theater Command | Leukemia | Details | |
| CTD-402 | CTD-402; CTD402 (CD7) | Phase 2 Clinical | Nanjing Bioheng Biotech Co Ltd | Precursor Cell Lymphoblastic Leukemia-Lymphoma | Details |
| CD5/CD7-Specific CAR-T Cells therapy(Essen Biotech) | BAH246; BAH-246; EB-BH2026 | Phase 2 Clinical | Essen Biotech | Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, Prolymphocytic, T-Cell; Lymphoma, T-Cell; Central Nervous System Diseases; Leukemia, T-Cell | Details |
| Autologous and Donor-derived CD7 CAR-T Therapy(Beijing GoBroad Hospital) | Phase 2 Clinical | Beijing GoBroad Hospital | Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | Details | |
| CD7-CAR-T Cells Therapy | CD7-CART01 | Phase 2 Clinical | Bambino Gesu Hospital And Research Institute | Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | Details |
| Humanized CD7 CAR-T cells | Phase 2 Clinical | The First Affiliated Hospital Of Soochow University | Lymphoma, T-Cell | Details | |
| WU-CART-007 | WU-CART-007 | Phase 2 Clinical | Wugen Inc | Lymphoma, T-Cell, Peripheral; Enteropathy-Associated T-Cell Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Lymphoma, Primary Cutaneous Anaplastic Large Cell; Lymphoma, Extranodal NK-T-Cell; Sezary Syndrome; Lymphoma, Large-Cell, Anaplastic; Leukemia, Prolymphocytic, T-Cell; Lymphoma, T-Cell; Leukemia, Myeloid, Acute; Mycosis Fungoides; Leukemia, T-Cell; Angioimmunoblastic T-cell Lymphoma | Details |
| Anti-CD7 CAR T-cell therapy (Yake Biotechnology) | Phase 2 Clinical | Shanghai YaKe Biotechnology Co Ltd | Still's Disease, Adult-Onset; Hematologic Diseases; Leukemia; Osteochondrodysplasias; Dermatomyositis; Autoimmune Diseases; Neoplasms; Bone Marrow Failure Disorders; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Anemia, Aplastic; Colitis, Ulcerative; Lymphoma; Lymphoma, T-Cell; Crohn Disease; Leukemia, T-Cell | Details | |
| CD7.CAR/28zeta CAR T cells | Phase 1 Clinical | Baylor College Of Medicine | Lymphoma, T-Cell, Peripheral; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Sezary Syndrome; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell; Angioimmunoblastic T-cell Lymphoma; Leukemia, Prolymphocytic; Mycosis Fungoides | Details | |
| GC-027 | GC-027 | Phase 1 Clinical | Gracell Biotechnologies (Shanghai) Co Ltd | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | Details |
| MB-107(March Biosciences) | MB-107(March Biosciences) | Phase 1 Clinical | March Biosciences Inc | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Lymphoma, T-Cell | Details |
| INT-2104 | INT-2104 | Phase 1 Clinical | Interius BioTherapeutics Inc | Lymphoma, B-Cell; Hematologic Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma | Details |
| RD-13 | RD13-02; RD 13 02; RD-13; RD-13-01; CTD-401 | Phase 1 Clinical | Nanjing Bioheng Biotech Co Ltd | Hematologic Neoplasms; Hematologic Diseases; Neoplasms; Anemia, Aplastic; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Lymphoma, Extranodal NK-T-Cell | Details |
| Anti-CD7 Chimeric Antigen Receptor T-Cell therapy(Bioceltech Therapeutics) | BT-007 | Phase 1 Clinical | Gracell Biotechnologies (Shanghai) Co Ltd, Bioceltech Therapeutics Ltd | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | Details |
| BE CAR-7 | BE-CAR-7 | Phase 1 Clinical | Great Ormond Street Hospital For Children Nhs Foundation Trust | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, Prolymphocytic, T-Cell | Details |
| Anti-CD7 CAR-T cell Therapy (Shanghai Jiao Tong University Affiliated First People'S Hospital) | Phase 1 Clinical | Shanghai Jiao Tong University Affiliated First People'S Hospital | Lymphoma, T-Cell, Peripheral; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Lymphoma, Large-Cell, Anaplastic; Angioimmunoblastic T-cell Lymphoma | Details | |
| Anti-CD19/CD7 UCAR-T cell therapy (Gracell) | GC-502 | Phase 1 Clinical | Gracell Biotechnologies (Shanghai) Co Ltd | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Lymphoma, Non-Hodgkin | Details |
| CD7 CARvac T cell therapy | Phase 1 Clinical | Icell Gene Therapeutics (Int'L) Ltd | Hematologic Neoplasms; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Lymphoma | Details | |
| SenL-T7 CAR T Cells (Hebei Senlang Biological) | Senl-T7; Senl-T-7; SENL-101 | Phase 1 Clinical | Hebei Senlang Biological Technology Co Ltd | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Lymphoma, T-Cell; Leukemia, T-Cell | Details |
| PA3-17 | PA3-17; PA-3-17; PA3-17 (autologous) | Phase 1 Clinical | Persongen Anke Cell Technology Co Ltd, Persongen Biotherapeutics (Suzhou) Co Ltd | Hematologic Neoplasms; Lymphoma | Details |
| CD7 CAR-T cell therapy (Hebei Senlang Biotechnology) | Phase 1 Clinical | Hebei Senlang Biological Technology Co Ltd | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma | Details | |
| PCART7-CD3 | PCART7-CD3 | Clinical | National University Of Singapore | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | Details |
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