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Home PageAll MoleculesIntegrin alpha 5 beta 1
Integrin alpha 5 beta 1
Integrin alpha 5 beta 1 Overview
| English Name | Integrin alpha-5/beta-1 | Approved Drugs | 1 |
| Drugs in Clinical Trials | 4 | Target Synonym | Integrin alpha5beta1 |
| Highest Development Stage | Approved | ||
| English Name | Integrin alpha-5/beta-1 |
| Target Synonym | Integrin alpha5beta1 |
| Approved Drugs | 1 |
| Drugs in Clinical Trials | 4 |
| Highest Development Stage | Approved |
Integrin alpha 5 beta 1 Product List
- Product Category
Protein (3)
- Product Status
Launched (3)
- Species
Human (2)Cynomolgus (1)
- Tag
His Tag (2)His Tag & Avi Tag (1)
- Conjugate
Unconjugated (2)Biotin-labeled (1)
| Cat. No. | Species | Host | Product Description | Structure | Purity | Feature | Order Now |
|---|---|---|---|---|---|---|---|
HOT IT1-H52W5 |  Human | HEK293 | Human Integrin alpha 5 beta 1 (ITGA5&ITGB1) Heterodimer Protein, His Tag&Tag Free, low endotoxin |  |  |  |  Add to Cart |
IT1-H82Wa | Human | HEK293 | Biotinylated Human Integrin alpha 5 beta 1 (ITGA5&ITGB1) Heterodimer Protein, His,Avitag™&Tag Free |  | | | Add to Cart |
IT1-C52W7 |  Cynomolgus | HEK293 | Cynomolgus Integrin alpha 5 beta 1 (ITGA5&ITGB1) Heterodimer Protein, His Tag&Tag Free (MALS verified) |  | | | Add to Cart |
Total: 3
- 1
Integrin alpha 5 beta 1 Background
Integrin alpha 5 beta 1 / Integrin α5β1, which is a major cellular receptor for the extracellular matrix protein fibronectin and plays a fundamental role during mammalian development., is composed of α5 (ITGA5/CD49e) and β1 (ITGB1/CD29) subunits. Integrins are adhesion receptors that transmit bidirectional signals across the plasma membrane. The Integrin alpha 5 beta 1 and its primary extracellular matrix ligand fibronectin (Fn) are of great biological importance.
Integrin alpha 5 beta 1 Synonyms
Integrin alpha 5 beta 1,ITGA5&ITGB1
Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| Risuteganib | ALG-1001; AM011; AM-011(Allegro Ophthalmics) | Phase 1 Clinical | Allegro Ophthalmics Llc | Diabetic macular oedema; Diabetic Retinopathy; Geographic Atrophy; Macular Degeneration | Details |
| Pegylated recombinant human endostatin (Tsinghua University) | M-2ES; CRB-0401 | Phase 1 Clinical | Beijing Proji Pharmaceutical Technology Co Ltd, Beijing Protgen Biotechnology Development Co Ltd, Tsinghua University | Carcinoma, Non-Small-Cell Lung; Neoplasms; Pancreatic Neoplasms; Solid tumours | Details |
| VAX-014 | VAX-014 | Phase 1 Clinical | Vaxiion Therapeutics Llc | Solid tumours | Details |
| Integrin α5β1 therapy (Eli Lilly and Company) | Phase 1 Clinical | Eli Lilly And Company | Cardiovascular Diseases | Details |
Marketed Drug Information
| English Name | Research Code | Highest Development Stage | Company | Earliest Brand Name | Earliest Approval Country | Earliest Indication | Earliest Approval Company | Earliest Approval Date | Indication | Clinical Trial |
|---|---|---|---|---|---|---|---|---|---|---|
| Recombinant human endostatin (Simcere) | YH-16 | Approved | Jiangsu Simcere Pharmaceutical Co Ltd | Endostar, 恩度, Endu | Mainland China | Carcinoma, Non-Small-Cell Lung | Shandong Xiansheng Zaiming Biopharmaceutical Co Ltd | 2005-09-12 | Ascites; Brain metastases; Carcinoma, Non-Small-Cell Lung; Esophageal Neoplasms; Head and Neck Neoplasms; Nasopharyngeal Carcinoma; Osteosarcoma; Pleural Effusion, Malignant | Details |
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