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Your Position: Home > TSLP

TSLP

TSLP Molecule Information

Name:Thymic stromal lymphopoietin
Target Synonym:TSLP

Number of Launched Drugs:0
Number of Drugs in Clinical Trials:2
Lastest Research Phase:Phase ?

TSLP Protein Product ListCompare or Buy

Product> Filter Results

Cat. No.	Species	Product Description
TSP-C52H8	Cynomolgus	Cynomolgus TSLP Protein, His Tag
TSP-C52H4	Cynomolgus	Cynomolgus TSLP (R127A, R130S) Protein, His Tag
TSP-M52H8	Mouse	Mouse TSLP Protein, His Tag
TSP-H5255	Human	Human TSLP (R127A, R130A) Protein, Mouse IgG2a Fc Tag
TSP-H82E0	Human	Biotinylated Human TSLP (R127A, R130A) Protein, His,Avitag™
TSP-H52Ha	Human	Human TSLP (R127A, R130A) Protein, His Tag
TSP-H52Hb	Human	Human TSLP Protein, His Tag
TSP-H82Eb	Human	Biotinylated Human TSLP Protein, His,Avitag™

TSLP Part of Bioactivity data

TSP-H52Ha-SPR

Captured Human TSLP (R127A, R130A), His Tag (Cat. No. TSP-H52Ha) on CM5 Chip via anti-His antibody, can bind Human TSLP R, Fc Tag (Cat. No. TSR-H525a) with an affinity constant of 4.22 nM as determined in SPR assay (Biacore T200) (Routinely tested).

Protocol

TSP-H52Hb-SPR

Captured Human TSLP, His Tag (Cat. No. TSP-H52Hb) on CM5 Chip via anti-His antibody, can bind Human TSLP R, Fc Tag (Cat. No. TSR-H525a) with an affinity constant of 1.81 nM as determined in SPR assay (Biacore T200) (Routinely tested).

Protocol

TSLP Molecule Synonym Name

TSLP

TSLP Molecule Background

Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine involved in the pathology of inflammatory skin diseases, and is widely expressed by epithelial cells. Human TSLP cDNA encodes a 159 amino acid (aa) residue precursor protein with a 28 aa signal sequence (4, 5). Human TSLP has been shown to developing nondeletional central tolerance, amplifying epithelium-induced class switching, inducing atopic diseases and maintaining intestinal noninflammatory environment. Among diverse cells responding to Human TSLP, CD11c+ dendritic cells are the most obviously characterized target cells.