0
There is no goods in the shopping cart !
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Home > TSLP

TSLP

TSLP Molecule Information

Name:Thymic stromal lymphopoietin
Target Synonym:TSLP
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:2
Lastest Research Phase:Phase ?

TSLP Part of Bioactivity data

TSP-H52Ha-SPR
Human_FcRn_Heterodimer_Protein_SPR

Captured Human TSLP (R127A, R130A), His Tag (Cat. No. TSP-H52Ha) on CM5 Chip via anti-His antibody, can bind Human TSLP R, Fc Tag (Cat. No. TSR-H525a) with an affinity constant of 4.22 nM as determined in SPR assay (Biacore T200) (Routinely tested).

TSP-H52Hb-SPR
Human_FcRn_Heterodimer_Protein_SPR

Captured Human TSLP, His Tag (Cat. No. TSP-H52Hb) on CM5 Chip via anti-His antibody, can bind Human TSLP R, Fc Tag (Cat. No. TSR-H525a) with an affinity constant of 1.81 nM as determined in SPR assay (Biacore T200) (Routinely tested).

TSLP Protein Product ListCompare or Buy

TSLP Molecule Synonym Name

TSLP

TSLP Molecule Background

Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine involved in the pathology of inflammatory skin diseases, and is widely expressed by epithelial cells. Human TSLP cDNA encodes a 159 amino acid (aa) residue precursor protein with a 28 aa signal sequence (4, 5). Human TSLP has been shown to developing nondeletional central tolerance, amplifying epithelium-induced class switching, inducing atopic diseases and maintaining intestinal noninflammatory environment. Among diverse cells responding to Human TSLP, CD11c+ dendritic cells are the most obviously characterized target cells.

TSLP References

TSLP Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
RG-7258 RG-7258 Phase Ⅰ Roche Asthma Details
Tezepelumab AMG-157; MEDI-9929 Phase Ⅲ Amgen, AstraZeneca Asthma Details

This web search service is supported by Google Inc.

totop