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Your Position: Home > IL-1 Rrp2

IL-1 Rrp2

Brief Information

Name:Interleukin-36 receptor
Target Synonym:Interleukin-1 Receptor-Related Protein 2,Interleukin-1 Receptor-Like 2,IL-1Rrp2,Interleukin 1 Receptor Like 2,EC:3.2.2.6,IL-36R,IL1RRP2,IL-36 Receptor,IL1R-Rp2,IL1RL2,IL-1 Receptor-Related Protein 2
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:3
Lastest Research Phase:NDA/BLA

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Part of Bioactivity data

IL2-H52H4-ELISA
Human IL-1 Rrp2 (C154S, C262S), His TagHuman IL-1 Rrp2 (C154S, C262S), His Tag (Cat. No. IL2-H52H4) ELISA bioactivity

Immobilized Anti-IL36R Antibody, Human IgG1 at 1 μg/mL (100 μL/well) can bind Human IL-1 Rrp2 (C154S, C262S), His Tag (Cat. No. IL2-H52H4) with a linear range of 4-125 ng/mL (QC tested).

IL2-H52H4-MALS-HPLC
Human IL-1 Rrp2 (C154S, C262S), His Tag (Cat. No. ) MALS images

The purity of Human IL-1 Rrp2 (C154S, C262S), His Tag(Cat. No. IL2-H52H4) is more than 90% and the molecular weight of this protein is around 50-65 kDa verified by SEC-MALS.

Bioactivity-ELISA
Human IL-1 Rrp2 (C154S, C262S), His TagHuman IL-1 Rrp2 (C154S, C262S), His Tag (Cat. No. IL2-H52H4) ELISA bioactivity

Immobilized Anti-IL36R Antibody, Human IgG1 at 1 μg/mL (100 μL/well) can bind Human IL-1 Rrp2 (C154S, C262S), His Tag (Cat. No. IL2-H52H4) with a linear range of 4-125 ng/mL (QC tested).

Synonym Name

IL-1 R6,IL-1 Rrp2,IL1RL2,IL-1RL2,IL1Rrp2,IL-1Rrp2,IL1RRP2,IL-36R

Background

The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9).  All family members possess three immunoglobulin (Ig)-like domains in their extracellular region. Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor signaling) domain that is also conserved in the Toll-like receptor family. Related proteins, SIGIRR (single Ig domain-containing IL-1 R-related molecule) and IL-18BP, differ from the other members by having only one Ig domain.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
HB-0034 HB-0034 Phase 1 Clinical Shanghai Huaota Biopharmaceutical Co Ltd Psoriasis Details

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