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Adalimumab

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Cat. No. Species Product Description Structure Purity Feature
ADB-Y23b Mouse Anti-Adalimumab Antibodies (AY23b) (recommended for PK/PD)
ADB-Y23b-sds
ADB-Y23b-elisa_1
ADB-Y19 Mouse Anti-Adalimumab Antibodies (AY19)
ADB-Y19-sds
ADB-Y19-elisa_1
ADB-Y19-elisa_2

Part of Bioactivity data

ADB-Y19-SPR
Human_FcRn_Heterodimer_Protein_SPR

Anti-Adalimumab Antibodies (mouse IgG1, Cat. No. ADB-Y19) captured on CM5 chip via anti-mouse antibodies surface, can bind human adalimumab with an affinity constant of 1.36 pM.

ADB-Y19-ELISA
Anti-Adalimumab AntibodiesAnti-Adalimumab Antibodies (Cat. No. ADB-Y19) ELISA bioactivity

Anti-Adalimumab Antibodies bridging ELISA for Anti-Drug Antibody (ADA) assay development.Immobilized adalimumab at 1 µg/mL, add increasing concentrations of Anti-Adalimumab Antibodies (Cat. No. ADB-Y19, 10% human serum) and then add biotinylated adalimumab at 5 µg/mL. Detection was performed using HRP-conjugated streptavidin with a sensitivity of 0.6 ng/mL.

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Background

Adalimumab is a human monoclonal antibody against TNF-alpha. It is produced by recombinant DNA technology using a mammalian cell expression system. It consists of 1330 amino acids and has a molecular weight of approximately 148 kilodaltons.

Clinical and Translational Updates

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