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CLEC12A

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CLEC12A Part of Bioactivity data

CLA-HF247-Cell-based assay
FACS assay shows that recombinant Biotinylated FACS

2e5 of Anti-CLEC12A CAR-293 cells were stained with 100 μL of 10 μg/mL of FITC-Labeled Human CLEC12A, His Tag (Cat. No. CLA-HF247) and negative control protein respectively. FITC signal was used to evaluate the binding activity (QC tested).

CLA-H5266-ELISA
Human CLEC12A, Fc TagHuman CLEC12A, Fc Tag (Cat. No. CLA-H5266) ELISA bioactivity

Immobilized Human CLEC12A, Fc Tag (Cat. No. CLA-H5266) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Human CLEC12A Antibody, Human IgG1 with a linear range of 0.1-4 ng/mL (QC tested).

CLA-H5245-ELISA
Human CLEC12A, His TagHuman CLEC12A, His Tag (Cat. No. CLA-H5245) ELISA bioactivity

Immobilized Human CLEC12A, His Tag (Cat. No. CLA-H5245) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Human CLEC12A Antibody, Human IgG1 with a linear range of 0.1-4 ng/mL (QC tested).

CLEC12A Molecule Synonym Name

CLEC12A,MICL,CLL-1,CLL1,DCAL2,DCAL-2,CD371

CLEC12A Molecule Background

CLEC12A (C-type lectin domain family 12 member A) is also known as CLL1, DCAL2, MICL. Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death. Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. Evidence of distinct disease propagating stem cells in myelodysplastic syndrome (MDS) has emerged in recent years.  The role of CLEC12A in MDS, however, remains to be elucidated. Furthermore, CLEC12A has been proposed as a promising marker of leukaemic stem cells in AML.

CLEC12A References

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