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5e5 of Anti-CLEC12A/CLL-1 CAR-293 cells were stained with 100 μL of 1:25 dilution (4 μL stock solution in 100 μL FACS buffer) of PE-Labeled Human CLEC12A / MICL / CLL-1 Protein, His Tag (C-terminus) (Cat. No. CLA-HP2H4) and negative control protein respectively. PE signal was used to evaluate the binding activity (QC tested).
5e5 of Anti-CLEC12A/CLL-1 CAR-293 cells were stained with 100 μL of 1:25 dilution (4 μL stock solution in 100 μL FACS buffer) of APC-Labeled Human CLEC12A Protein, His Tag, premium grade (Cat. No. CLA-HA246) and negative control protein respectively. APC signal was used to evaluate the binding activity (QC tested).
Loaded Monoclonal Anti-Human CLEC12A Antibody, Human IgG1 on Protein A Biosensor, can bind Human CLEC12A, His Tag (Cat. No. CLA-H5245) with an affinity constant of 131 nM as determined in BLI assay (ForteBio Octet R8) (Routinely tested).
Immobilized Biotinylated Human CLEC12A Protein, His,Avitag (Cat. No. CLA-H82E9) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Monoclonal Anti-Human CLEC12A Antibody, Human IgG1 with a linear range of 0.1-2 ng/mL (QC tested).
| Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
|---|---|---|---|---|---|
| ARD-103 | ARD-103; ARD103 | Phase 2 Clinical | ARCE Therapeutics Inc | Myelodysplastic Syndromes; Leukemia, Myeloid, Acute | Details |
| Anti-CLL1 CAR-T (Guangzhou Bio-Gene) | BG-1805; BG1805 | Phase 2 Clinical | Guangzhou Bio-Gene Technology Co Ltd | Leukemia; Leukemia, Myeloid, Acute | Details |
| Anti-CLL1 CAR T cell therapy(Soochow University) | Phase 2 Clinical | The First Affiliated Hospital Of Soochow University | Leukemia, Myeloid, Acute | Details | |
| ICG-136 | ICG-136; 123b-33bcCAR | Phase 1 Clinical | Icell Gene Therapeutics (Int'L) Ltd | Leukemia, Myeloid, Acute | Details |
| CLL-1.CAR T cell therapy (Baylor College of Medicine) | Phase 1 Clinical | Baylor College Of Medicine | Leukemia, Myeloid, Acute | Details | |
| CB-012(Caribou Biosciences) | CB-012 | Phase 1 Clinical | Caribou Biosciences Inc | Leukemia, Myeloid, Acute | Details |
| QL-325 | QL-325 | Phase 1 Clinical | Qilu Pharmaceutical Co Ltd, Qlsf Biotherapeutics Inc | Leukemia, Myeloid, Acute | Details |
| Anti-CLL-1 CAR NK cells Therapy(Shanghai General Hospital) | Phase 1 Clinical | Shanghai Jiao Tong University Affiliated First People'S Hospital | Leukemia, Myeloid, Acute | Details | |
| CLL1 and CD38 Dual CAR-T therapy(Gracell Biotechnologies) | Phase 1 Clinical | Gracell Biotechnologies (Shanghai) Co Ltd | Leukemia, Myeloid, Acute | Details | |
| Universal CAR-T Cells therapy(Shenzhen Geno-Immune Medical Institute) | Phase 1 Clinical | Shenzhen Geno-Immune Medical Institute | Leukemia, Myeloid, Acute | Details | |
| CLL1 CAR-NK cell (Zhejiang University/Hangzhou Qihangene Biotech) | Phase 1 Clinical | Zhejiang University, Hangzhou Qihan Jiyin Biotechnology Co Ltd | Leukemia, Myeloid, Acute | Details | |
| CD33/CLL1 dual CAR-NK cell therapy (Hangzhou Qihan) | Phase 1 Clinical | Hangzhou Qihan Biotechnology Co Ltd | Neoplasm, Residual; Leukemia, Myeloid, Acute | Details | |
| CD371-YSNVZ-IL18 CAR T cells therapy | Phase 1 Clinical | Memorial Sloan Kettering Cancer Center | Leukemia, Myeloid, Acute | Details | |
| ADCLEC.syn1 CAR T cells therapy (Memorial Sloan-Kettering Cancer Center) | Phase 1 Clinical | Memorial Sloan Kettering Cancer Center | Leukemia, Myeloid, Acute | Details | |
| IBR-733 | IBR-733; IBR733 | Phase 1 Clinical | Imbioray (Hangzhou) Biomedicine Co Ltd | Leukemia, Myeloid, Acute | Details |
| CLL1 CAR-T(Zhejiang University) | Phase 1 Clinical | Zhejiang University | Leukemia, Myeloid, Acute | Details | |
| CLL1+CD33 CAR-T(Zhejiang University) | Phase 1 Clinical | Zhejiang University | Leukemia, Myeloid, Acute | Details | |
| CLL1 CAR T-cell Therapy(Yake Biotechnology) | Phase 1 Clinical | Shanghai YaKe Biotechnology Co Ltd | Leukemia, Myeloid, Acute | Details | |
| Anti-CD33/CLL-1 CAR-T (Legend) | Phase 1 Clinical | Legend Biotech Corp | Leukemia, Promyelocytic, Acute | Details |
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