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Your Position: Home > Protein > IDO1 > ID1-H5143

Human IDO1 Protein, His Tag

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This product is still under development. Please contact us if you have interest in this product. We will accelerate the development process accordingly and reserve this product for you as request.
  • Synonym
    IDO, IDO-1, INDO
  • Source
    Human IDO1 Protein, His Tag(ID1-H5143) is expressed from E. coli cells. It contains AA Ala 2 - Gly 403 (Accession # P14902-1).
    Predicted N-terminus: Met
  • Molecular Characterization
    IDO1 Structure

    This protein carries a polyhistidine tag at the N-terminus

    The protein has a calculated MW of 47.1 kDa.

  • Formulation

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Background
    This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.
  • Clinical and Translational Updates

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Price(USD) : $350.00

Price(USD) : $2500.00

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Drug Development Status

  • Number of Launched Drugs:0 Details
  • Number of Drugs in Clinical Trials:14 Details
  • Latest Research Phase:Phase 3 Clinical

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