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Your Position: Home > Protein > GLP1R > GLR-H52D5

Human GLP1R Protein, Flag,His Tag (Detergent)

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  • Synonym
    GLP-1, GLP-1-R, GLP-1R, glucagon like peptide 1 receptor
  • Source
    Human GLP1R Protein, Flag,His Tag(GLR-H52D5) is expressed from human 293 cells (HEK293). It contains AA Arg 24 - Ser 432 (Accession # P43220-1).
    Predicted N-terminus: Met
  • Molecular Characterization
    GLP1R Structure

    This protein carries flag tag at the N-terminus and polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 67.0 kDa.

  • Formulation

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
  • Background
    This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke.
  • Clinical and Translational Updates

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  • Number of Launched Drugs:0 Details
  • Number of Drugs in Clinical Trials:1 Details
  • Latest Research Phase:Phase 1 Clinical

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